This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ABCA1 Polyclonal Antibody, DyLight 650
catalog :
PA5-22907
quantity :
100 uL
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
DyLight 650
reactivity :
Chinese hamsters, human, mouse, rat, dogs, chicken, pigs , domestic rabbit, domestic horse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
Product Type :
Antibody
Product Name :
ABCA1 Polyclonal Antibody, DyLight 650
Catalog # :
PA5-22907
Quantity :
100 uL
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Canine, Chicken, Equine, Hamster, Human, Mouse, Mustelid, Non-human primate, Porcine, Rabbit, Rat
Applications :
ELISA: Assay-Dependent, Flow Cytometry: 1:10-1:1,000, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:500
Species :
Canine, Chicken, Equine, Hamster, Human, Mouse, Mustelid, Non-human primate, Porcine, Rabbit, Rat
Isotype :
IgG
Storage :
4 C, store in dark
Description :
Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
Immunogen :
Partial peptide sequence (peptide used resides somewhere between a.a 1100-1300) of the human ABCA1 gene. Actual immunogen sequence is proprietary information.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-Dependent, Flow Cytometry: 1:10-1:1,000, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:500
Aliases :
ABC 1; ABC 1 antibody; ABC Transporter 1; Abc1; ABC-1; ABC1 antibody; Abca1; ATP binding cassette subfamily A member 1; ATP-binding cassette 1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ATP-binding cassette transporter A1; ATP-binding cassette, subfamily A (ABC1), member 1; ATP-binding cassette, sub-family A (ABC1), member 1; ATP-binding cassette, sub-family A member 1; CERP; CERP antibody; Cholesterol efflux regulatory protein; HDLDT1; membrane-bound; phospholipid-transporting ATPase ABCA1; phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; TGD
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA