Nurr1 Polyclonal Antibody | Invitrogen PA5-22830 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nurr1 Polyclonal Antibody

catalog :

PA5-22830

quantity :

100 ug

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

Nurr1 Polyclonal Antibody

Catalog # :

PA5-22830

Quantity :

100 ug

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Rat

Applications :

Immunohistochemistry (PFA fixed): 1:100-1:200, Immunoprecipitation: Assay-Dependent, Western Blot: 1:500-1:2,000

Species :

Human, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The Nuclear receptor related 1 protein (Nurr1) also known as NR4A2 (nuclear receptor subfamily 4, group A, member 2) is a protein that in humans is encoded by the NR4A2 gene. NURR1 is a member of the nuclear receptor family of intracellular transcription factors.Nurr1 plays a key role in the maintenance of the dopaminergic system of the brain. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's disease, schizophrenia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full-length nature has not been determined.

Immunogen :

Synthetic peptide comprising residues 513-526 of the human Nurr1 protein. Based on 100% sequence homology, this antibody is also expected to cross react with rat and mouse Nurr1.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (PFA fixed): 1:100-1:200, Immunoprecipitation: Assay-Dependent, Western Blot: 1:500-1:2,000

Aliases :

HZF3; Hzf-3; Immediate-early response protein NOT; intermediate-early receptor protein; NGFI-B; NGFI-B beta; NGFI-B/nur77 beta-type transcription factor homolog; NOT; NR4A2; Nuclear orphan receptor HZF-3; nuclear receptor related 1; nuclear receptor subfamily 4 group A member 2; nuclear receptor subfamily 4 group A member 2 variant TINUR; nuclear receptor subfamily 4 group A member 2 variant NURR1a; nuclear receptor subfamily 4 group A member 2 variant NURR1b; nuclear receptor subfamily 4 group A member 2 variant NURR1c; nuclear receptor subfamily 4 group A member 2 variant NURR2c; nuclear receptor subfamily 4, group A, member 2; nur related protein 1; nur related protein-1, human homolog of; Nurr1; NUR-related factor 1; orphan nuclear receptor NR4A2; orphan nuclear receptor NURR1; Regenerating liver nuclear receptor 1; RNR1; RNR-1; SL-322; T-cell nuclear receptor NOT; TINOR; TINUR; transcriptionally inducible nuclear receptor related 1; transcriptionally-inducible nuclear receptor