product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
JAM2 Polyclonal Antibody
catalog :
PA5-21576
quantity :
100 µL
price :
US 470
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 2
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; rat; 1:100-1:200; loading ...; fig 3f
Redmond S, Mei F, Eshed Eisenbach Y, Osso L, Leshkowitz D, Shen Y, et al. Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination. Neuron. 2016;91:824-836 pubmed publisher
Day Walsh P, Keeble B, Pirabagar G, Fountain S, Kroon P. Transcriptional and Post-Translational Regulation of Junctional Adhesion Molecule-B (JAM-B) in Leukocytes under Inflammatory Stimuli. Int J Mol Sci. 2022;23: pubmed publisher
image
image 1 :
Invitrogen PA5-21576 image 1
Immunohistochemical analysis of paraffin-embedded TOV-112D xenograft tissue using PA5-21576 anti-JAM-B antibody at 1:100 dilution.
product information
Product Type :
Antibody
Product Name :
JAM2 Polyclonal Antibody
Catalog # :
PA5-21576
Quantity :
100 µL
Price :
US 470
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
Species :
Human
Isotype :
IgG
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
Immunogen :
Recombinant fragment corresponding to a region within amino acids 1 and 294 of JAM-B (Uniprot ID#P57087)
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
Aliases :
1110002N23Rik; 2410030G21Rik; 2410167M24Rik; AU016127; C21orf43; CD322; Jam2; JAM-2; JAMB; JAM-B; JAM-IT/VE-JAM; Jcam2; junction adhesion molecule 2; junction adhesion molecule B; junction cell adhesion molecule 2; junctional adhesion molecule 2; Junctional adhesion molecule B; PRO245; RP23-253E17.2; UNQ219/PRO245; Vascular endothelial junction-associated molecule; VEJAM; VE-JAM
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA