ZIP14 Polyclonal Antibody | Invitrogen PA5-21077 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ZIP14 Polyclonal Antibody

catalog :

PA5-21077

quantity :

100 ug

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 2c	Sterling J, Guttha S, Song Y, Song D, Hadziahmetovic M, Dunaief J. Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels. Exp Eye Res. 2017;155:15-23 pubmed publisher
	Di J, Chen Z, Wang Z, He T, Wu D, Weng C, et al. Cartilage tissue from sites of weight bearing in patients with osteoarthritis exhibits a differential phenotype with distinct chondrocytes subests. RMD Open. 2023;9: pubmed publisher
	Protic I, Golic I, Vidaković S, Korac B, Korac A. Heterogeneous Immunolocalisation of Zinc Transporters ZIP6, ZIP10 and ZIP14 in Human Normo- and Asthenozoospermic Spermatozoa. Curr Issues Mol Biol. 2022;44:3444-3454 pubmed publisher
	Sterling J, Kam T, Guttha S, Park H, Baumann B, Mehrabani Tabari A, et al. Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein. Cell Rep. 2022;38:110358 pubmed publisher
	Ding H, Chen S, Pan X, Dai X, Pan G, Li Z, et al. Transferrin receptor 1 ablation in satellite cells impedes skeletal muscle regeneration through activation of ferroptosis. J Cachexia Sarcopenia Muscle. 2021;12:746-768 pubmed publisher
	Lawson R, Maret W, Hogstrand C. Prolonged stimulation of insulin release from MIN6 cells causes zinc depletion and loss of β-cell markers. J Trace Elem Med Biol. 2018;49:51-59 pubmed publisher
	Hendrickx G, Borra V, Steenackers E, Yorgan T, Hermans C, Boudin E, et al. Conditional mouse models support the role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in bone homeostasis. PLoS Genet. 2018;14:e1007321 pubmed publisher
	Olgar Y, Durak A, Tuncay E, Bitirim C, Ozcinar E, Inan M, et al. Increased free Zn2+ correlates induction of sarco(endo)plasmic reticulum stress via altered expression levels of Zn2+ -transporters in heart failure. J Cell Mol Med. 2018;22:1944-1956 pubmed publisher
	Olgar Y, Ozdemir S, Turan B. Induction of endoplasmic reticulum stress and changes in expression levels of Zn2+-transporters in hypertrophic rat heart. Mol Cell Biochem. 2018;440:209-219 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ZIP14 Polyclonal Antibody

Catalog # :

PA5-21077

Quantity :

100 ug

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1-2 ug/mL, Western Blot: 1-4 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Maintain refrigerated at 2-8 C for up to 3 months. For long term storage store at -20 C

Description :

The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.

Immunogen :

A peptide corresponding to 16 amino acid synthetic peptide near the center of human ZIP14. The immunogen is located within amino acids 230-280 of ZIP14.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1-2 ug/mL, Western Blot: 1-4 ug/mL

Aliases :

cig19; Factor for adipocyte differentiation 123; Fad123; FAD-123; HMNDYT2; Kiaa0062; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; NET34; SLC39A14; solute carrier family 39 (metal ion transporter), member 14; solute carrier family 39 (zinc transporter), member 14; solute carrier family 39 member 14; Zinc transporter ZIP14; Zip14; ZIP-14; Zrt- and Cig19; Zrt- and Irt-like protein 14; Zrt-, Irt-like protein 14

more info or order :

Invitrogen product webpage