c-Raf Polyclonal Antibody | Invitrogen PA5-20970 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

c-Raf Polyclonal Antibody

catalog :

PA5-20970

quantity :

100 ug

price :

US 474.00

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

Product Type :

Antibody

Product Name :

c-Raf Polyclonal Antibody

Catalog # :

PA5-20970

Quantity :

100 ug

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Chicken

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot: 0.5-1.0 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgY

Storage :

Maintain refrigerated at 2-8 C for up to 3 months. For long term storage store at -20 C

Description :

Raf-1 (c-Raf) is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

Immunogen :

an 19 amino acid peptide near the amino terminus of human C-raf.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 0.5-1.0 ug/mL

Aliases :

6430402F14Rik; AA990557; BB129353; CMD1NN; CRAF; C-RAF; C-Raf proto-oncogene, serine/threonine kinase; Craf1; Craf1 transforming; D830050J10Rik; EC 2.7.11.1; kinase Raf1; murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV); murine sarcoma 3611 oncogene 1; NS5; Oncogene RAF1; OTTHUMP00000207813; OTTHUMP00000209389; proto-oncogene c-RAF; RAF; raf proto-oncogene serine/threonine protein kinase; RAF proto-oncogene serine/threonine-protein kinase; RAF1; Raf-1; Raf-1 proto-oncogene, serine/threonine kinase; sarcoma 3611 oncogene; v-Raf; v-raf-1 leukemia viral oncogene 1; vraf1 murine le; v-raf-1 murine leukemia viral oncogene homolog 1; v-raf-1 murine leukemia viral oncogene-like protein 1; v-raf-leukemia viral oncogene 1