KCNK18 Polyclonal Antibody | Invitrogen PA5-20873 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KCNK18 Polyclonal Antibody

catalog :

PA5-20873

quantity :

100 ug

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

KCNK18 Polyclonal Antibody

Catalog # :

PA5-20873

Quantity :

100 ug

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 20 ug/mL, Immunohistochemistry: 5 ug/mL, Western Blot: 1-2 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Maintain refrigerated at 2-8 C for up to 3 months. For long term storage store at -20 C

Description :

TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.

Immunogen :

A 17 amino acid peptide from near the center of human TRESK.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 20 ug/mL, Immunohistochemistry: 5 ug/mL, Western Blot: 1-2 ug/mL

Aliases :

2P K ion channel TRESK; Gm781; K2p18.1; Kcnk18; MGR13; Potassium channel subfamily K member 18; potassium channel, subfamily K, member 18; potassium channel, two pore domain subfamily K, member 18; potassium two pore domain channel subfamily K member 18; tandem-pore K+ (K(2P)) channel; Tresk; TRESK2; Tresk-2; TRIK; TWIK-related individual K+ channel; TWIK-related individual potassium channel; TWIK-related spinal cord K+ channel; TWIK-related spinal cord potassium channel; Two-pore-domain potassium channel TRESK