This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SIPA1L2 Polyclonal Antibody
catalog :
PA5-20848
quantity :
100 ug
price :
US 454.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
citations: 1
Reference
Ke X, Liao Z, Luo X, Chen J, Deng M, Huang Y, et al. Endothelial colony-forming cell-derived exosomal miR-21-5p regulates autophagic flux to promote vascular endothelial repair by inhibiting SIPL1A2 in atherosclerosis. Cell Commun Signal. 2022;20:30 pubmed publisher
product information
Product Type :
Antibody
Product Name :
SIPA1L2 Polyclonal Antibody
Catalog # :
PA5-20848
Quantity :
100 ug
Price :
US 454.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunohistochemistry: 5 ug/mL, Western Blot: 0.5-1 ug/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
Maintain refrigerated at 2-8 C for up to 3 months. For long term storage store at -20 C
Description :
Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.
Immunogen :
A 19 amino acid peptide from near the amino terminus of human SIPA1L2.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry: 5 ug/mL, Western Blot: 0.5-1 ug/mL
Aliases :
BC058408; Kiaa0545; KIAA1389; mKIAA1389; serine-rich synapse associated protein 2; serine-rich synapse-associated protein; Sersap2; signal induced proliferation associated 1 like 2; signal-induced proliferation-associated 1 like 2; signal-induced proliferation-associated 1-like protein 2; Sipa1l2; SIPA1-like protein 2; SPA-1-like 2; SPAL2; Spar2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA