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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SQSTM1 Polyclonal Antibody
catalog :
PA5-20839
quantity :
100 ug
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; fig 3
Mukherjee R, Chakrabarti O. Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis. J Cell Sci. 2016;129:757-73 pubmed publisher
Duan J, Zhang Q, Zhu J, Lu J. Curcumin affects autophagy of prolactinoma cells by upregulating miR-206 to exert antitumor effects. J Biochem Mol Toxicol. 2024;38:e23734 pubmed publisher
Alshaman R, Kolieb E, El Sayed R, Gouda S, Alattar A, Zaitone S, et al. Computational and Experimental Approaches Exploring the Role of Hesperetin in Improving Autophagy in Rat Diabetic Retinopathy. Biomedicines. 2024;12: pubmed publisher
Bu K, Kim M, Shin M, Lee S, Sung J. Regulation of Benzo[a]pyrene-Induced Hepatic Lipid Accumulation through CYP1B1-Induced mTOR-Mediated Lipophagy. Int J Mol Sci. 2024;25: pubmed publisher
Feng B, Yu P, Yu H, Qian B, Li Y, Sun K, et al. Therapeutic effects on the development of heart failure with preserved ejection fraction by the sodium-glucose cotransporter 2 inhibitor dapagliflozin in type 2 diabetes. Diabetol Metab Syndr. 2023;15:141 pubmed publisher
Masson J, Badran G, Domdom M, Gherardi R, Mograbi B, Authier F, et al. Advances on the early cellular events occurring upon exposure of human macrophages to aluminum oxyhydroxide adjuvant. Sci Rep. 2023;13:3198 pubmed publisher
Cristofani R, Piccolella M, Montagnani Marelli M, Tedesco B, Poletti A, Moretti R. HSPB8 counteracts tumor activity of BRAF- and NRAS-mutant melanoma cells by modulation of RAS-prenylation and autophagy. Cell Death Dis. 2022;13:973 pubmed publisher
Huang J, Linares J, Duran A, Xia W, Saltiel A, Müller T, et al. NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ. Nat Commun. 2021;12:2876 pubmed publisher
An Y, Liu H, Zhou Z, Wang J, Jiang G, Li Z, et al. Sinoporphyrin sodium is a promising sensitizer for photodynamic and sonodynamic therapy in glioma. Oncol Rep. 2020;44:1596-1604 pubmed publisher
Sunchu B, Riordan R, Yu Z, Almog I, Dimas Munoz J, Drake A, et al. Aggresome-Like Formation Promotes Resistance to Proteotoxicity in Cells from Long-Lived Species. J Gerontol A Biol Sci Med Sci. 2020;75:1439-1447 pubmed publisher
Masson J, Blanchet B, Periou B, Authier F, Mograbi B, Gherardi R, et al. Long Term Pharmacological Perturbation of Autophagy in Mice: Are HCQ Injections a Relevant Choice?. Biomedicines. 2020;8: pubmed publisher
Fontana F, Moretti R, Raimondi M, Marzagalli M, Beretta G, Procacci P, et al. δ-Tocotrienol induces apoptosis, involving endoplasmic reticulum stress and autophagy, and paraptosis in prostate cancer cells. Cell Prolif. 2019;52:e12576 pubmed publisher
Nazim U, Park S. Attenuation of autophagy flux by 6-shogaol sensitizes human liver cancer cells to TRAIL-induced apoptosis via p53 and ROS. Int J Mol Med. 2019;43:701-708 pubmed publisher
Fauzia E, Barbhuyan T, Shrivastava A, Kumar M, Garg P, Khan M, et al. Chick Embryo: A Preclinical Model for Understanding Ischemia-Reperfusion Mechanism. Front Pharmacol. 2018;9:1034 pubmed publisher
Cristofani R, Montagnani Marelli M, Cicardi M, Fontana F, Marzagalli M, Limonta P, et al. Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells. Cell Death Dis. 2018;9:889 pubmed publisher
Kose M, Demir S, Akinci G, Eraslan C, Yilmaz U, Ceylaner S, et al. The Second Case of Saposin A Deficiency and Altered Autophagy. JIMD Rep. 2019;44:43-54 pubmed publisher
Latomanski E, Newton H. Interaction between autophagic vesicles and the Coxiella-containing vacuole requires CLTC (clathrin heavy chain). Autophagy. 2018;14:1710-1725 pubmed publisher
Mitsui S, Otomo A, Nozaki M, Ono S, Sato K, Shirakawa R, et al. Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model. Mol Brain. 2018;11:30 pubmed publisher
Kaul Z, Chakrabarti O. Tumor susceptibility gene 101 regulates predisposition to apoptosis via ESCRT machinery accessory proteins. Mol Biol Cell. 2017;28:2106-2122 pubmed publisher
Majumder P, Chakrabarti O. Mahogunin regulates fusion between amphisomes/MVBs and lysosomes via ubiquitination of TSG101. Cell Death Dis. 2015;6:e1970 pubmed publisher
product information
Product Type :
Antibody
Product Name :
SQSTM1 Polyclonal Antibody
Catalog # :
PA5-20839
Quantity :
100 ug
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 20 ug/mL, Immunohistochemistry (Paraffin): 2-5 ug/mL, Immunohistochemistry (PFA fixed): 20 ug/mL, Western Blot: 0.5-2 ug/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
4 C
Description :
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Immunogen :
A 13 amino acid synthetic peptide from near the carboxy terminus of human SQSTM1. The immunogen is located within the last 50 amino acids of SQSTM1.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 20 ug/mL, Immunohistochemistry (Paraffin): 2-5 ug/mL, Immunohistochemistry (PFA fixed): 20 ug/mL, Western Blot: 0.5-2 ug/mL
Aliases :
A170; EBI3-associated protein of 60 kDa; EBI3-associated protein p60; EBIAP; FTDALS3; hypothetical protein 1; ORCA; OSF-6; Osi; OSIL; oxidative stress induced; oxidative stress induced like; p60; p62; p62B; PDB3; phosphotyrosine independent ligand for the Lck SH2 domain p62; phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; PKC-zeta-interacting protein; protein kinase C-zeta-interacting protein; sb:cb621; Sequestosome 1; sequestosome-1; Sqstm1; STAP; STONE14; ubiquitin-binding protein p62; Unknown (protein for MGC:127197); zgc:85784; ZIP; ZIP3
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA