ATOH8 Polyclonal Antibody | Invitrogen PA5-20710 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ATOH8 Polyclonal Antibody

catalog :

PA5-20710

quantity :

100 µg

price :

US 456.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, zebrafish

application :

western blot, immunohistochemistry

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; zebrafish ; 1:250; loading ...; fig 2a	Place E, Smith J. Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes. PLoS ONE. 2017;12:e0171143 pubmed publisher
	George J, Martin Diaz L, Ojanen M, Gasa R, Pesu M, Viiri K. PRC2 Regulated Atoh8 Is a Regulator of Intestinal Microfold Cell (M Cell) Differentiation. Int J Mol Sci. 2021;22: pubmed publisher

product information

Product Type :

Antibody

Product Name :

ATOH8 Polyclonal Antibody

Catalog # :

PA5-20710

Quantity :

100 µg

Price :

US 456.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry: 5 µg/mL, Western Blot: 1-2 µg/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Description :

Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. ATOH8 (MATH6) is a tissue-restricted member of the atonal superfamily of bHLH transcription factors that exhibits 43-57% identity in the bHLH domain with other mammalian atonal paralogs including the NeuroD and Neurogenin factors. In the mouse, ATOH8 has been implicated in the specification and differentiation of neuronal cell lineages in the brain and may also participate in kidney development. Recent studies show that ATOH8 is a novel component of the pancreatic transcriptional network during embryonic development and suggest a potential role as a modulator of the differentiation program initiated by the pro-endocrine factor Neurog3. It is indispensable for early embryonic development, suggesting a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes.

Immunogen :

A 15 amino acid peptide near the carboxy terminus of human ATOH8.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 5 µg/mL, Western Blot: 1-2 µg/mL

Aliases :

4933425C05Rik; Ath6; Atoh8; atonal bHLH transcription factor 8; atonal homolog 6; atonal homolog 8; atonal homolog 8 (Drosophila); atonal homolog bHLH transcription factor 8; basic helix loop helix transcription factor 6; basic helix-loop-helix transcription factor 6; bHLHa21; Class A basic helix-loop-helix protein 21; hATH6; Helix-loop-helix protein hATH-6; helix-loop-helix protein mATH-6; mATH6; Okadin; Protein atonal homolog 8; RGD1561512

more info or order :

Invitrogen product webpage