SLC22A17 Polyclonal Antibody | Invitrogen PA5-20543 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SLC22A17 Polyclonal Antibody

catalog :

PA5-20543

quantity :

100 ug

price :

US 481.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

citations: 3

Reference
Meyers K, Lopez M, Ho J, Wills S, Rayalam S, Taval S. Lipocalin-2 deficiency may predispose to the progression of spontaneous age-related adiposity in mice. Sci Rep. 2020;10:14589 pubmed publisher
Rehwald C, Schnetz M, Urbschat A, Mertens C, Meier J, Bauer R, et al. The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma. Br J Cancer. 2020;122:421-433 pubmed publisher
Garrido Arandia M, Tome Amat J, Pazos Castro D, Esteban V, Escribese M, Hernández Ramírez G, et al. Interaction of Alt a 1 with SLC22A17 in the airway mucosa. Allergy. 2019;74:2167-2180 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SLC22A17 Polyclonal Antibody

Catalog # :

PA5-20543

Quantity :

100 ug

Price :

US 481.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry: 2.5 ug/mL, Western Blot: 0.5 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Maintain refrigerated at 2-8 C for up to 3 months. For long term storage store at -20 C

Description :

The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predominantly in kidney and liver. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.

Immunogen :

A 14 amino acid peptide near the carboxy terminus of the human Slc22A17.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 2.5 ug/mL, Western Blot: 0.5 ug/mL

Aliases :

1700094C23Rik; 24p3 receptor; 24p3R; AU041908; AW555662; BOCT; Boit; brain-specific organic ion transporter; brain-type organic cation transporter; hBOIT; Lipocalin-2 receptor; mBOCT; Neutrophil gelatinase-associated lipocalin receptor; NGAL receptor; NgalR; NGALR2; NGALR3; organic cation transporter BOCT; potent brain type organic ion transporter; rBOCT; SLC22A17; solute carrier family 22 (organic cation transporter), member 17; solute carrier family 22 member 17; solute carrier family 22, member 17