IEX-1 Polyclonal Antibody | Invitrogen PA5-20391 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IEX-1 Polyclonal Antibody

catalog :

PA5-20391

quantity :

100 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

IEX-1 Polyclonal Antibody

Catalog # :

PA5-20391

Quantity :

100 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 20 ug/mL, Immunohistochemistry: 2.5 ug/mL, Western Blot: 1-2 ug/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

4 C

Description :

IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-a. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-kappa-B/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression.

Immunogen :

A 24 amino acid peptide near the center of human IEX1.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 20 ug/mL, Immunohistochemistry: 2.5 ug/mL, Western Blot: 1-2 ug/mL

Aliases :

AI663993; anti-death protein; cAMP inducible gene 3; cI-3; DADB-118P11.5; Dif2; DIF-2; differentiation-dependent gene 2 protein; expressed in pancreatic carcinoma; GLY96; gly96, mouse, homolog of; IER3; IEX1; IEX-1; IEX-1L; immediate early protein GLY96; immediate early response 3; immediate early response 3 protein; immediately early gene X-1; Ler3; PACAP-responsive gene 1 protein; PRG1; Protein DIF-2; Protein PRG1; Radiation-inducible immediate-early gene IEX-1