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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TLR9 Polyclonal Antibody
catalog :
PA5-20203
quantity :
100 ug
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
Invitrogen product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; fig 6
He J, Johnson J, Monfregola J, Ramadass M, Pestonjamasp K, Napolitano G, et al. Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses. Mol Biol Cell. 2016;27:572-87 pubmed publisher
  • western blot; mouse; fig 1
Johnson J, He J, Ramadass M, Pestonjamasp K, Kiosses W, Zhang J, et al. Munc13-4 Is a Rab11-binding Protein That Regulates Rab11-positive Vesicle Trafficking and Docking at the Plasma Membrane. J Biol Chem. 2016;291:3423-38 pubmed publisher
Ishikawa T, Abe K, Takana Ishikawa M, Yoshida K, Watanabe T, Imakiire S, et al. Chronic Inhibition of Toll-Like Receptor 9 Ameliorates Pulmonary Hypertension in Rats. J Am Heart Assoc. 2021;10:e019247 pubmed publisher
Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher
product information
Product Type :
Antibody
Product Name :
TLR9 Polyclonal Antibody
Catalog # :
PA5-20203
Quantity :
100 ug
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 2 ug/mL, Western Blot: 1.0 ug/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
4 C
Description :
The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Immunogen :
A peptide corresponding to 15 amino acids near the center of human TLR9.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2 ug/mL, Western Blot: 1.0 ug/mL
Aliases :
CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA