Bim Polyclonal Antibody | Invitrogen PA5-20089 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Bim Polyclonal Antibody

catalog :

PA5-20089

quantity :

100 µg

price :

US 446.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 7	Garg N, Tyagi R, Singh B, Sharma G, Nirbhavane P, Kushwah V, et al. Nanostructured lipid carrier mediates effective delivery of methotrexate to induce apoptosis of rheumatoid arthritis via NF-ÎºB and FOXO1. Int J Pharm. 2016;499:301-320 pubmed publisher
	Arjunan P, Meghil M, Pi W, Xu J, Lang L, El Awady A, et al. Oral Pathobiont Activates Anti-Apoptotic Pathway, Promoting both Immune Suppression and Oncogenic Cell Proliferation. Sci Rep. 2018;8:16607 pubmed publisher
	Tyagi R, Miles B, Parmar R, Garg N, Dalai S, Baban B, et al. Human IDO-competent, long-lived immunoregulatory dendritic cells induced by intracellular pathogen, and their fate in humanized mice. Sci Rep. 2017;7:41083 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Bim Polyclonal Antibody

Catalog # :

PA5-20089

Quantity :

100 µg

Price :

US 446.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 10 µg/mL, Western Blot: 5 µg/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Description :

BIM belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

Immunogen :

A peptide corresponding to amino acids near the center of human Bim

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 10 µg/mL, Western Blot: 5 µg/mL

Aliases :

1500006F24Rik; BAM; Bcl2 interacting mediator of cell death; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; BCL2 like 11; Bcl-2 like 11; Bcl-2 related apoptotic gene product BimL; bcl2-interacting mediator of cell death; BCL2L11; Bcl2-L-11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; bcl-2-like protein 11-like; bcl-2-related ovarian death agonist; bcl-2-related ovarian death protein; BIM; Bim EL; Bim-A; BIM-alpha6; BIM-beta6; BIM-beta7; BIMEL; BimEL protein; BimL; BOD; OTTHUMP00000197013; OTTHUMP00000204247; Unknown (protein for MGC:134444)

more info or order :

Invitrogen product webpage