MD-2 Polyclonal Antibody | Invitrogen PA5-20058 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MD-2 Polyclonal Antibody

catalog :

PA5-20058

quantity :

100 ug

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Zhang Q, Xu S, Qian J, Yang L, Chen P, Wang Y, et al. Pharmacological inhibition of MyD88 suppresses inflammation in tubular epithelial cells and prevents diabetic nephropathy in experimental mice. Acta Pharmacol Sin. 2022;43:354-366 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MD-2 Polyclonal Antibody

Catalog # :

PA5-20058

Quantity :

100 ug

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 2-2.5 ug/mL, Immunohistochemistry (PFA fixed): 10-20 ug/mL, Western Blot: 0.5-1 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

4 C

Description :

MD-2 is a gene that encodes a protein involved in the recognition of bacterial lipopolysaccharides (LPS) by the immune system. It is located on chromosome 8 and is part of a larger family of genes that encode for similar proteins. The MD-2 protein forms a complex with Toll-like receptor 4 (TLR4) to recognize and respond to LPS, triggering an immune response. Mutations or variations in the MD-2 gene have been associated with various diseases and conditions, including sepsis and inflammatory disorders.

Immunogen :

A peptide corresponding to amino acids near the middle region of human MD-2.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 2-2.5 ug/mL, Immunohistochemistry (PFA fixed): 10-20 ug/mL, Western Blot: 0.5-1 ug/mL

Aliases :

Esop1; ESOP-1; LPS co-receptor MD-2; LY96; ly-96; Lymphocyte antigen 96; MD2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2