APAF1 Polyclonal Antibody | Invitrogen PA5-19894 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

APAF1 Polyclonal Antibody

catalog :

PA5-19894

quantity :

100 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 8	Bugueno I, Khelif Y, Seelam N, Morand D, Tenenbaum H, Davideau J, et al. Porphyromonas gingivalis Differentially Modulates Cell Death Profile in Ox-LDL and TNF-α Pre-Treated Endothelial Cells. PLoS ONE. 2016;11:e0154590 pubmed publisher
	Can O, Canat L, Eraldemir F, Acar E, Yildirim F, Sönmez K, et al. Protective effect of oltipraz in testicular ischaemia/reperfusion injury: An experimental study. Andrologia. 2022;54:e14245 pubmed publisher
	Bugueno I, Batool F, Korah L, Benkirane Jessel N, Huck O. Porphyromonas gingivalis Differentially Modulates Apoptosome Apoptotic Peptidase Activating Factor 1 in Epithelial Cells and Fibroblasts. Am J Pathol. 2018;188:404-416 pubmed publisher

product information

Product Type :

Antibody

Product Name :

APAF1 Polyclonal Antibody

Catalog # :

PA5-19894

Quantity :

100 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry: 20 ug/mL, Western Blot: 1 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Maintain refrigerated at 2-8 C for up to 3 months. For long term storage store at -20 C

Description :

APAF1 gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.

Immunogen :

A peptide corresponding to amino acids near the carboxy terminus of human Apaf1

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 20 ug/mL, Western Blot: 1 ug/mL

Aliases :

6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413

more info or order :

Invitrogen product webpage