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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
KCNN2 Polyclonal Antibody
catalog :
PA5-19205
quantity :
100 ug
price :
US 474.00
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 1a
Willis M, Trieb M, Leitner I, Wietzorrek G, Marksteiner J, Knaus H. Small-conductance calcium-activated potassium type 2 channels (SK2, KCa2.2) in human brain. Brain Struct Funct. 2017;222:973-979 pubmed publisher
product information
Product Type :
Antibody
Product Name :
KCNN2 Polyclonal Antibody
Catalog # :
PA5-19205
Quantity :
100 ug
Price :
US 474.00
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation
Host :
Goat
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 2-4 ug/mL, Western Blot: 0.3-1 ug/mL
Species :
Human
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Action potentials in vertebrate neurons are followed by an afterhyperpolarization that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen :
Synthetic peptide sequence (ESYDKHVTYNAER) corresponding to the internal amino acids of KCNN2 (aa 545-558).
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 2-4 ug/mL, Western Blot: 0.3-1 ug/mL
Aliases :
apamin-sensitive small-conductance Ca2+-activated potassium channel; fri; hSK2; KCa2.2; KCNN2; potassium calcium-activated channel subfamily N member 2; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2; potassium intermediate/small conductance calcium-activated channel type2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; SK2; SKCa 2; SKCa2; small conductance calcium-activated channel, subfamily N, member 2; small conductance calcium-activated potassium channel 2; small conductance calcium-activated potassium channel protein 2; small conductance calcium-activated potassium channel protein 2-like; small conductance calcium-activated potassium channel subfamily N member 2; small conductance potassium channel type 2; small conductance potassium channel type2; small conductance potassium channel type2 variant2
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA