This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
P2X7 Polyclonal Antibody
catalog :
PA5-19165
quantity :
100 ug
price :
US 470.00
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 1
Reference
Baeza Raja B, Goodyear A, Liu X, Lam K, Yamamoto L, Li Y, et al. Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis. PLoS ONE. 2020;15:e0234038 pubmed publisher
product information
Product Type :
Antibody
Product Name :
P2X7 Polyclonal Antibody
Catalog # :
PA5-19165
Quantity :
100 ug
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation
Host :
Goat
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 10 ug/mL, Immunohistochemistry (Paraffin): 3-6 ug/mL, Western Blot: 1-3 ug/mL
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay criteria.
Immunogen :
Synthetic peptide sequence (YETNKVTRIQSMNY) corresponding to the N-terminus amino acids of P2RX7 (aa 13-27).
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 10 ug/mL, Immunohistochemistry (Paraffin): 3-6 ug/mL, Western Blot: 1-3 ug/mL
Aliases :
AI467586; ATP receptor; MGC20089; P2rx7; P2X purinoceptor 7; p2X receptor 7; P2X(7); P2X7; P2X7 purinoceptor; P2X7 receptor; P2X7R; P2Z; P2Z receptor; Purinergic receptor; purinergic receptor P2X 7; purinergic receptor P2X, ligand gated ion channel, 7; purinergic receptor P2X, ligand-gated ion channel, 7; purinergic receptor P2X7; purinergic receptor P2X7 variant A
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA