ZO-1 Polyclonal Antibody | Invitrogen PA5-19090 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ZO-1 Polyclonal Antibody

catalog :

PA5-19090

quantity :

100 ug

price :

US 562.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

immunocytochemistry

citations: 6

Reference
R xfc land L, Andreatta F, Massalini S, Chuva de Sousa Lopes S, Clevers H, Hendriks D, et al. Organoid models of fibrolamellar carcinoma mutations reveal hepatocyte transdifferentiation through cooperative BAP1 and PRKAR2A loss. Nat Commun. 2023;14:2377 pubmed publisher
Veit J, Birru B, Singh R, Arrigali E, Serban M. An In Vitro Model for Characterization of Drug Permeability across the Tympanic Membrane. Pharmaceuticals (Basel). 2022;15: pubmed publisher
Singh R, Birru B, Veit J, Arrigali E, Serban M. Development and Characterization of an In Vitro Round Window Membrane Model for Drug Permeability Evaluations. Pharmaceuticals (Basel). 2022;15: pubmed publisher
Afanasyeva T, Corral Serrano J, Garanto A, Roepman R, Cheetham M, Collin R. A look into retinal organoids: methods, analytical techniques, and applications. Cell Mol Life Sci. 2021;78:6505-6532 pubmed publisher
Bluhmki T, Bitzer S, Gindele J, Schruf E, Kiechle T, Webster M, et al. Development of a miniaturized 96-Transwell air-liquid interface human small airway epithelial model. Sci Rep. 2020;10:13022 pubmed publisher
Hebeda C, Sandri S, Benis C, Paula Silva M, Loiola R, Reutelingsperger C, et al. Annexin A1/Formyl Peptide Receptor Pathway Controls Uterine Receptivity to the Blastocyst. Cells. 2020;9: pubmed publisher

product information

Product Type :

Antibody

Product Name :

ZO-1 Polyclonal Antibody

Catalog # :

PA5-19090

Quantity :

100 ug

Price :

US 562.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Goat

Reactivity :

Human

Applications :

Immunocytochemistry: 10 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.

Immunogen :

Synthetic peptide sequence (PKPTSQNQFSEHDKT) corresponding to the internal amino acids of TJP1 (aa 1308-1323).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 10 ug/mL

Aliases :

DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1