Ferritin Heavy Chain Polyclonal Antibody | Invitrogen PA5-19058 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Ferritin Heavy Chain Polyclonal Antibody

catalog :

PA5-19058

quantity :

100 ug

price :

US 514.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry

citations: 2

Reference
Shieh J, Tintos Hernandez J, Murali C, Penon Portmann M, Flores Méndez M, Santana A, et al. Heterozygous nonsense variants in the ferritin heavy-chain gene FTH1 cause a neuroferritinopathy. HGG Adv. 2023;4:100236 pubmed publisher
Shieh J, Tintos Hern xe1 ndez J, Murali C, Penon Portmann M, Flores Méndez M, Santana A, et al. Heterozygous Nonsense Variants in the Ferritin Heavy Chain Gene FTH1 Cause a Novel Pediatric Neuroferritinopathy. medRxiv. 2023;: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Ferritin Heavy Chain Polyclonal Antibody

Catalog # :

PA5-19058

Quantity :

100 ug

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Goat

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100, Western Blot: 1-3 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

Immunogen :

Synthetic peptide sequence (DKHTLGDSDNES) corresponding to the C-terminus amino acids of FTH1 (aa 172-183).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Western Blot: 1-3 ug/mL

Aliases :

apoferritin; cell proliferation-inducing gene 15 protein; Ferritin H subunit; ferritin heavy chain; ferritin heavy chain 1; Ferritin heavy chain, N-terminally processed; Ferritin subunit H; ferritin, heavy polypeptide 1; FHC; frih; FTH; Fth1; FTHL6; HFE5; H-ferritin; HFt; MFH; MGC104426; OK/SW-cl.84; PIG15; placenta immunoregulatory factor; PLIF; proliferation-inducing protein 15