FBXO32 Polyclonal Antibody | Invitrogen PA5-19056 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FBXO32 Polyclonal Antibody

catalog :

PA5-19056

quantity :

100 ug

price :

US 470.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 2b	Meshram S, Paul D, Manne R, Choppara S, Sankaran G, Agrawal Y, et al. FBXO32 activates NF-ÎºB through IÎºBÎ± degradation in inflammatory and genotoxic stress. Int J Biochem Cell Biol. 2017;92:134-140 pubmed publisher
	Emmert M, Aggarwal P, Shay Winkler K, Lee S, Goh Q, Cornwall R. Sex-specific role of myostatin signaling in neonatal muscle growth, denervation atrophy, and neuromuscular contractures. elife. 2022;11: pubmed publisher
	Seldeen K, Pang M, Leiker M, Bard J, Rodríguez Gonzalez M, Hernández M, et al. Chronic vitamin D insufficiency impairs physical performance in C57BL/6J mice. Aging (Albany NY). 2018;10:1338-1355 pubmed publisher

product information

Product Type :

Antibody

Product Name :

FBXO32 Polyclonal Antibody

Catalog # :

PA5-19056

Quantity :

100 ug

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Goat

Reactivity :

Mouse

Applications :

Western Blot: 0.3-1 ug/mL

Species :

Mouse

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs, which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.

Immunogen :

Synthetic peptide sequence (NSKTKTQYFHQEK) corresponding to the internal amino acids of FBXO32 (aa 70-83).

Format :

Liquid

Applications w/Dilutions :

Western Blot: 0.3-1 ug/mL

Aliases :

4833442G10Rik; AI430017; atrogin 1; atrogin1; atrogin-1; atrophy gene 1; F-box only protein 32; F-box protein 32; Fbx32; fbxo25; FBXO32; FLJ32424; Gm20361; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F-box protein; similar to F-box only protein 32 isoform 1; zgc:56479

more info or order :

Invitrogen product webpage