DGAT2 Polyclonal Antibody | Invitrogen PA5-18667 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DGAT2 Polyclonal Antibody

catalog :

PA5-18667

quantity :

100 ug

price :

US 454.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Govatati S, Pichavaram P, Mani A, Kumar R, Sharma D, Dienel A, et al. Novel role of xanthine oxidase-dependent H2O2 production in 12/15-lipoxygenase-mediated de novo lipogenesis, triglyceride biosynthesis and weight gain. Redox Biol. 2021;47:102163 pubmed publisher

product information

Product Type :

Antibody

Product Name :

DGAT2 Polyclonal Antibody

Catalog # :

PA5-18667

Quantity :

100 ug

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Goat

Reactivity :

Human

Applications :

Flow Cytometry: 10 ug/mL, Immunohistochemistry (Paraffin): 3 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism.

Immunogen :

Synthetic peptide sequence (KLEHPTQQDIDLYH) corresponding to the internal amino acids of DGAT2 (aa 346-360).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 10 ug/mL, Immunohistochemistry (Paraffin): 3 ug/mL

Aliases :

0610010B06Rik; Acyl-CoA retinol O-fatty-acyltransferase; ARAT; DGAT2; DGAT-2; diacylglycerol acyltransferase 2; diacylglycerol O-acyltransferase 2; diacylglycerol O-acyltransferase homolog 2; diacylglycerol O-acyltransferase-like protein 2; diglyceride acyltransferase 2; DKFZp686A15125; GS1999FULL; HMFN1045; LOW QUALITY PROTEIN: diacylglycerol O-acyltransferase 2; putative diacylglycerol O-acyltransferase; retinol O-fatty-acyltransferase; UNQ738/PRO1433