GPX1 Polyclonal Antibody | Invitrogen PA5-18532 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GPX1 Polyclonal Antibody

catalog :

PA5-18532

quantity :

100 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic goat

conjugate :

HRP

reactivity :

human, pigs

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

product information

Product Type :

Antibody

Product Name :

GPX1 Polyclonal Antibody

Catalog # :

PA5-18532

Quantity :

100 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Goat

Reactivity :

Human, Porcine

Applications :

Immunohistochemistry (Frozen): 20 ug/mL, Immunohistochemistry (Paraffin): 3-5 ug/mL, Immunohistochemistry (PFA fixed): 3-5 ug/mL, Western Blot: 1-3 ug/mL

Species :

Human, Porcine

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.

Immunogen :

Synthetic peptide sequence (REALPAPSDDATA) corresponding to the internal amino acids of GPX1 (aa 130-142).

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): 20 ug/mL, Immunohistochemistry (Paraffin): 3-5 ug/mL, Immunohistochemistry (PFA fixed): 3-5 ug/mL, Western Blot: 1-3 ug/mL

Aliases :

AI195024; AL033363; Cellular glutathione peroxidase; CGPx; cytosolic glutathione peroxidase; glutathione peroxidase; glutathione peroxidase 1; Gpx; Gpx1; GPx-1; GPXD; GSHPx; GSHPX1; GSHPx-1; HGNC:4553; MGC14399; MGC88245; OTTHUMP00000210766; Selenium-dependent glutathione peroxidase 1