MRP4 Polyclonal Antibody | Invitrogen PA5-18315 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MRP4 Polyclonal Antibody

catalog :

PA5-18315

quantity :

100 ug

price :

US 474.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 3

Reference
Kryczka J, Kryczka J, Janczewski x, Gajda A, Fr x105 czyk A, Boncela J, et al. Isothiocyanates (ITCs) 1-(Isothiocyanatomethyl)-4-phenylbenzene and 1-Isothiocyanato-3,5-bis(trifluoromethyl)benzene-Aldehyde Dehydrogenase (ALDH) Inhibitors, Decreases Cisplatin Tolerance and Migratory Ability of NSCLC. Int J Mol Sci. 2022;23: pubmed publisher
Kryczka J, Sochacka E, Papiewska Pajak I, Boncela J. Implications of ABCC4-Mediated cAMP Eflux for CRC Migration. Cancers (Basel). 2020;12: pubmed publisher
Zhang J, Wei Y, Min J, Wang Y, Yin L, Cao G, et al. Knockdown of RAP2A gene expression suppresses cisplatin resistance in gastric cancer cells. Oncol Lett. 2020;19:350-358 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MRP4 Polyclonal Antibody

Catalog # :

PA5-18315

Quantity :

100 ug

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Goat

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 4-6 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.

Immunogen :

Synthetic peptide sequence (CNGQPSTLTIFETAL) corresponding to the C-terminus amino acids of ABCC4 (aa 1316-1325).

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 4-6 ug/mL

Aliases :

ABCC4; ABC-tranporter; ATP binding cassette subfamily C member 4; ATP-binding cassette protein C4; ATP-binding cassette sub-family C member 4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); D630049P08Rik; EST170205; MOATB; MOAT-B; MRP/cMOAT-related ABC transporter; MRP4; Multidrug resistance-associated protein 4; multi-specific organic anion transporter B; RP11-74A12.1