Alpha-Smooth Muscle Actin Polyclonal Antibody | Invitrogen PA5-18292 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Alpha-Smooth Muscle Actin Polyclonal Antibody

catalog :

PA5-18292

quantity :

100 ug

price :

US 478.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

citations: 12

Reference
Senatus L, Ega xf1 a Gorro xf1 o L, L xf3 pez D xed ez R, Bergaya S, Aranda J, Amengual J, et al. DIAPH1 mediates progression of atherosclerosis and regulates hepatic lipid metabolism in mice. Commun Biol. 2023;6:280 pubmed publisher
Sacrist xe1 n G xf3 mez P, Serrano Somavilla A, Castro Espadas L, S xe1 nchez de la Blanca Carrero N, Sampedro N xfa xf1 ez M, Mu xf1 oz De Nova J, et al. Evaluation of Epithelial-Mesenchymal Transition Markers in Autoimmune Thyroid Diseases. Int J Mol Sci. 2023;24: pubmed publisher
Subbaiah K, Wu J, Tang W, Yao P. Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis. J Cardiovasc Dev Dis. 2023;10: pubmed publisher
Ordo xf1 o J, P xe9 rez Amodio S, Ball K, Aguirre A, Engel E. The generation of a lactate-rich environment stimulates cell cycle progression and modulates gene expression on neonatal and hiPSC-derived cardiomyocytes. Biomater Adv. 2022;139:213035 pubmed publisher
McEnaney R, McCreary D, Skirtich N, Andraska E, Sachdev U, Tzeng E. Elastic Laminar Reorganization Occurs with Outward Diameter Expansion during Collateral Artery Growth and Requires Lysyl Oxidase for Stabilization. Cells. 2021;11: pubmed publisher
Ruetten H, Sandhu J, Mueller B, Wang P, Zhang H, Wegner K, et al. A uropathogenic E. coli UTI89 model of prostatic inflammation and collagen accumulation for use in studying aberrant collagen production in the prostate. Am J Physiol Renal Physiol. 2021;320:F31-F46 pubmed publisher
Zhao Q, Liu J, Deng H, Ma R, Liao J, Liang H, et al. Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output. Cell. 2020;183:76-93.e22 pubmed publisher
Ruetten H, Cole C, Wehber M, Wegner K, Girardi N, Peterson N, et al. An immunohistochemical prostate cell identification key indicates that aging shifts procollagen 1A1 production from myofibroblasts to fibroblasts in dogs prone to prostate-related urinary dysfunction. PLoS ONE. 2020;15:e0232564 pubmed publisher
Voicu G, Rebleanu D, Constantinescu C, Fuior E, Ciortan L, Droc I, et al. Nano-Polyplexes Mediated Transfection of Runx2-shRNA Mitigates the Osteodifferentiation of Human Valvular Interstitial Cells. Pharmaceutics. 2020;12: pubmed publisher
Raselli T, Wyss A, Gonzalez Alvarado M, Weder B, Mamie C, Spalinger M, et al. The Oxysterol Synthesising Enzyme CH25H Contributes to the Development of Intestinal Fibrosis. J Crohns Colitis. 2019;13:1186-1200 pubmed publisher
Selvarajah B, Azuelos I, Platè M, Guillotin D, Forty E, Contento G, et al. mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1-induced collagen biosynthesis. Sci Signal. 2019;12: pubmed publisher
Almquist B, Castleberry S, Sun J, Lu A, Hammond P. Combination Growth Factor Therapy via Electrostatically Assembled Wound Dressings Improves Diabetic Ulcer Healing In Vivo. Adv Healthc Mater. 2015;4:2090-2099 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Alpha-Smooth Muscle Actin Polyclonal Antibody

Catalog # :

PA5-18292

Quantity :

100 ug

Price :

US 478.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Goat

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot: 0.1-1 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Smooth Muscle Actin belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actin being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. In particular, smooth muscle actin is an alpha actin that is found in skeletal muscle. Actin exists as a ubiquitous protein involved with filament formation that make up large portions of the cytoskeleton. Actin filaments interact with myosin to assist in muscle contraction as well as aiding in cell motility and cytokinesis. Smooth muscle actin is found on smooth muscle vessel walls, gut wall, myometrium, myoepithelial cells in breast and salivary glands. Defects in the smooth muscle actin gene cause aortic aneurysm familial thoracic type 6. Actin isoforms differ slightly in their N-terminus and the sequences of each are perfectly conserved in higher vertebrates. Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells. In addition, it has also been shown that smooth muscle actin appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases. Multiple alternatively spliced variants of smooth muscle actin have been identified.

Immunogen :

Synthetic peptide sequence (EEEDSTALVC) corresponding to the N-terminus amino acids of ACTA2 (aa 3-12).

Format :

Liquid

Applications w/Dilutions :

Western Blot: 0.1-1 ug/mL

Aliases :

0610041G09Rik; AAT6; ACT-4; acta2; acta2.L; acta2.S; actin; Actin Alpha 2 Smooth Muscle Aorta; actin alpha 2, smooth muscle; Actin Vascular Smooth Muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha 2, smooth muscle, aorta L homeolog; actin, alpha 2, smooth muscle, aorta S homeolog; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha actin 2; Alpha Cardiac Actin; alpha smooth muscle actin; alpha-actin; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-SM-actin; alpha-smooth muscle actin; Aortic Smooth Muscle; asma; a-sma; cell growth-inhibiting gene 46 protein; GIG46; Growth Inhibiting Gene 46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, aortic smooth muscle; mymy5; SM actin; sma; SMactin; sm-actin; SMalphaA; smooth muscle; smooth muscle alpha-actin; vascular smooth muscle alpha-actin; wu:fb63d03; XELAEV_18034370mg