Kalirin Polyclonal Antibody | Invitrogen PA5-18214 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Kalirin Polyclonal Antibody

catalog :

PA5-18214

quantity :

100 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Lu W, Chao H, Lin P, Lin S, Liu T, Chen H, et al. CPEB3-dowregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice. Neuropsychopharmacology. 2021;46:1669-1679 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Kalirin Polyclonal Antibody

Catalog # :

PA5-18214

Quantity :

100 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Goat

Reactivity :

Human

Applications :

Flow Cytometry: 10 ug/mL, Immunohistochemistry (Paraffin): 4-5 ug/mL, Western Blot: 0.1 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

HAP1 (huntingtin-associated protein 1) binds to huntingtin. Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington's disease (HD). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region. HAP1 shows neuronal localization and moves with huntingtin in nerve fibers. HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem. Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons. Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.

Immunogen :

Synthetic peptide sequence (RWHLGPGDPFSTYV) corresponding to the C-terminus amino acids of KALRN (aa 1641-1654).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 10 ug/mL, Immunohistochemistry (Paraffin): 4-5 ug/mL, Western Blot: 0.1 ug/mL

Aliases :

2210407G14Rik; ARHGEF24; AV235988; CHD5; CHDS5; cyclin B1; DUET; DUO; E530005C20Rik; FLJ12332; FLJ16443; FLJ18196; FLJ18623; Gm539; HAPIP; hCG_2022551; huntingtin-associated protein interacting protein (duo); huntingtin-associated protein-interacting protein; Kalirin; kalirin, RhoGEF kinase; kalrn; PAM COOH-terminal interactor protein 10; P-CIP10; Protein Duo; RhoGEF kinase; serine/threonine kinase with Dbl- and pleckstrin homology domain; serine/threonine kinase with Dbl- and pleckstrin homology domains; serine/threonine-protein kinase with Dbl- and pleckstrin homology domain; TRAD