NDRG1 Polyclonal Antibody | Invitrogen PA5-18109 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NDRG1 Polyclonal Antibody

catalog :

PA5-18109

quantity :

100 ug

price :

US 474.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Skedsmo F, Tranulis M, Espenes A, Prydz K, Matiasek K, Gunnes G, et al. Cell and context-dependent sorting of neuropathy-associated protein NDRG1 - insights from canine tissues and primary Schwann cell cultures. BMC Vet Res. 2019;15:121 pubmed publisher
Song Y, Wu G, Zhang M, Kong Q, Du J, Zheng Y, et al. N-myc downstream-regulated gene 1 inhibits the proliferation and invasion of hepatocellular carcinoma cells via the regulation of integrin ?3. Oncol Lett. 2017;13:3599-3607 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NDRG1 Polyclonal Antibody

Catalog # :

PA5-18109

Quantity :

100 ug

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Goat

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 2.5 ug/mL, Western Blot: 0.1-0.3 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

NDRG1 is a 394 amino acid cytoplasmic protein belonging to the NDRG family. It interacts with APO A-I and A-II and plays a role in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth and differentiation. Its defect causes Charcot-Marie-Tooth disease type 4D (CMT4D) that is characterized by reduced nerve conduction velocities, segmental demyelination and remyelination with onion bulb formations on nerve biopsy, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes and hollow feet. NDRG1 plays a growth inhibitory role and serves as a marker of differentiation. It is expressed in placental membranes, prostate, kidney, small intestine, ovary tissues, colon and the cells that border the lumen.

Immunogen :

Synthetic peptide sequence (GNSAGPKSMEVSC) corresponding to the C-terminus amino acids of NDRG1 (aa 382-394).

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 2.5 ug/mL, Western Blot: 0.1-0.3 ug/mL

Aliases :

CAP43; CMT4D; differentiation-related gene 1 protein; DRG1; DRG-1; GC4; HMSNL; Ndr1; Ndrg1; Ndrl; nickel-specific induction protein Cap43; NMSL; N-myc downstream regulated 1; N-myc downstream regulated gene 1; N-myc downstream-regulated gene 1 protein; Protein Ndr1; protein NDRG1; protein regulated by oxygen-1; PROXY1; Reducing agents and tunicamycin-responsive protein; Rit42; RTP; TARG1; TDD5