MAP2 Polyclonal Antibody | Invitrogen PA5-17646 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MAP2 Polyclonal Antibody

catalog :

PA5-17646

quantity :

100 uL

price :

US 460.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

citations: 20

Reference
Sun C, Seranova E, Cohen M, Chipara M, Roberts J, Astuti D, et al. NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency. Cell Rep. 2023;42:112372 pubmed publisher
Cruz E, Machado L, Zamproni L, Bim L, Ferreira P, Pinto L, et al. A Gelatin Methacrylate-Based Hydrogel as a Potential Bioink for 3D Bioprinting and Neuronal Differentiation. Pharmaceutics. 2023;15: pubmed publisher
Ye Q, Srivastava P, Al Kuwari N, Chen X. Oncogenic BRAFV600E induces microglial proliferation through extracellular signal-regulated kinase and neuronal death through c-Jun N-terminal kinase. Neural Regen Res. 2023;18:1613-1622 pubmed publisher
You Y, Hersh S, Aslebagh R, Shaffer S, Ikezu S, Mez J, et al. Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells. Aging Cell. 2022;21:e13617 pubmed publisher
Mateus J, Weaver S, van Swaay D, Renz A, Hengsteler J, Aguiar P, et al. Nanoscale Patterning of In Vitro Neuronal Circuits. ACS Nano. 2022;: pubmed publisher
Rothan H, Kumari P, Stone S, Natekar J, Arora K, Auroni T, et al. SARS-CoV-2 Infects Primary Neurons from Human ACE2 Expressing Mice and Upregulates Genes Involved in the Inflammatory and Necroptotic Pathways. Pathogens. 2022;11: pubmed publisher
Cai W, Srivastava P, Feng D, Lin Y, Vanderburg C, Xu Y, et al. Melanocortin 1 receptor activation protects against alpha-synuclein pathologies in models of Parkinson's disease. Mol Neurodegener. 2022;17:16 pubmed publisher
Du F, Yu Q, Kanaan N, Yan S. Mitochondrial oxidative stress contributes to the pathological aggregation and accumulation of tau oligomers in Alzheimer's disease. Hum Mol Genet. 2022;31:2498-2507 pubmed publisher
Dehkordi S, Walker J, Sah E, Bennett E, Atrian F, Frost B, et al. Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology. Nat Aging. 2021;1:1107-1116 pubmed publisher
Machiela E, Jeloka R, Caron N, Mehta S, Schmidt M, Baddeley H, et al. The Interaction of Aging and Cellular Stress Contributes to Pathogenesis in Mouse and Human Huntington Disease Neurons. Front Aging Neurosci. 2020;12:524369 pubmed publisher
Lin L, Xie J, Sánchez O, Bryan C, Freeman J, Yuan C. Low dose lead exposure induces alterations on heterochromatin hallmarks persisting through SH-SY5Y cell differentiation. Chemosphere. 2021;264:128486 pubmed publisher
Tristan C, Ormanoglu P, Slamecka J, Malley C, Chu P, Jovanovic V, et al. Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells. bioRxiv. 2020;: pubmed publisher
Bruno G, Colistra N, Melle G, Cerea A, Hubarevich A, Deleye L, et al. Microfluidic Multielectrode Arrays for Spatially Localized Drug Delivery and Electrical Recordings of Primary Neuronal Cultures. Front Bioeng Biotechnol. 2020;8:626 pubmed publisher
González Orozco J, Moral Morales A, Camacho Arroyo I. Progesterone through Progesterone Receptor B Isoform Promotes Rodent Embryonic Oligodendrogenesis. Cells. 2020;9: pubmed publisher
Young Baird S, Lourenço M, Elder M, Klann E, Liebau S, Dever T. Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB. Mol Cell. 2019;: pubmed publisher
Srinivasan S, Stevens C. Scaling Principles of Distributed Circuits. Curr Biol. 2019;29:2533-2540.e7 pubmed publisher
Duan T, Smith A, Verkman A. Complement-independent bystander injury in AQP4-IgG seropositive neuromyelitis optica produced by antibody-dependent cellular cytotoxicity. Acta Neuropathol Commun. 2019;7:112 pubmed publisher
Setoh Y, Amarilla A, Peng N, Griffiths R, Carrera J, Freney M, et al. Determinants of Zika virus host tropism uncovered by deep mutational scanning. Nat Microbiol. 2019;4:876-887 pubmed publisher
Paolillo M, Galiazzo M, Daga A, Ciusani E, Serra M, Colombo L, et al. An RGD small-molecule integrin antagonist induces detachment-mediated anoikis in glioma cancer stem cells. Int J Oncol. 2018;53:2683-2694 pubmed publisher
Jan A, Jansonius B, Delaidelli A, Somasekharan S, Bhanshali F, Vandal M, et al. eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response. Acta Neuropathol. 2017;133:101-119 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MAP2 Polyclonal Antibody

Catalog # :

PA5-17646

Quantity :

100 uL

Price :

US 460.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 1:50-1:100, Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

-20 C

Description :

MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).

Immunogen :

Synthetic peptide corresponding to carboxy-terminal residues of human MAP2

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:100, Western Blot: 1:1,000

Aliases :

a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2