This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PKA alpha Polyclonal Antibody
catalog :
PA5-17626
quantity :
100 uL
price :
US 514.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 5
Reference
Gao J, Li H, Xu H, Liu Y, Cai M, Shi Y, et al. High glucose-induced glucagon resistance and membrane distribution of GCGR revealed by super-resolution imaging. iScience. 2023;26:105967 pubmed publisher
Ba x148 as x, Benko F, x10e ura x10d ka M, Luk xe1 x10d N, Tvrd xe1 E. Epicatechin Prevents Cryocapacitation of Bovine Spermatozoa through Antioxidant Activity and Stabilization of Transmembrane Ion Channels. Int J Mol Sci. 2023;24: pubmed publisher
Semesta K, Garces A, Tsvetanova N. The psychosis risk factor RBM12 encodes a novel repressor of GPCR/cAMP signal transduction. bioRxiv. 2023;: pubmed publisher
Benko F, Fialkov xe1 V, x17d iarovsk xe1 J, x10e ura x10d ka M, Luk xe1 x10d N, Tvrd xe1 E. In Vitro versus Cryo-Induced Capacitation of Bovine Spermatozoa, Part 2: Changes in the Expression Patterns of Selected Transmembrane Channels and Protein Kinase A. Int J Mol Sci. 2022;23: pubmed publisher
Long X, Wu H, Zhou Y, Wan Y, Kan X, Gong J, et al. Preventive Effect of Limosilactobacillus fermentum SCHY34 on Lead Acetate-Induced Neurological Damage in SD Rats. Front Nutr. 2022;9:852012 pubmed publisher
product information
Product Type :
Antibody
Product Name :
PKA alpha Polyclonal Antibody
Catalog # :
PA5-17626
Quantity :
100 uL
Price :
US 514.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Flow Cytometry: 1:50-1:200, Immunocytochemistry: 1:50-1:100, Immunoprecipitation: 1:50, Western Blot: 1:1,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C
Description :
Protein kinase A (PKA, cAMP-dependent protein kinase) is a key element of a ubiquitous signaling pathway important in the cell cycle, cellular communication, memory formation and behavior. PKA is composed of two catalytic (PKAc; Protein Kinase A catalytic subunit) and two regulatory subunits (PKAr). Upon binding cAMP, the complex dissociates to PKAr dimer and two activated PKAc ser/thr protein kinase catalytic monomers. The released PKAc can translocate into the nucleus and exert a regulatory role in the activation of multiple nuclear hormone receptors. However, PKAc-mediated activation of tonicity-dependent gene expression is cAMP independent. Humans express three types of PKAc subunit - PKAc alpha is present in most human tissues, PKAc beta and gamma are tissue-specific, the later is found in testes.
Immunogen :
Synthetic peptide corresponding to the carboxy terminal sequence of human PKA C-a
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:50-1:200, Immunocytochemistry: 1:50-1:100, Immunoprecipitation: 1:50, Western Blot: 1:1,000
Aliases :
alternatively spliced; C(s); Calpha; C-alpha-2; C-alpha-S; cAMP-dependent protein kinase catalytic subunit alpha; cAMP-dependent protein kinase catalytic subunit alpha, isoform 1; cAMP-dependent protein kinase catalytic subunit C alpha; cAMP-dependent protein kinase catalytic subunit Calpha1; Cs-PKA; MGC102831; MGC48865; PKA; PKA C-alpha; PKA catalytic subunit alpha; pkac; Pkaca; PKCA1; PKCD; PPNAD4; PRKACA; protein kinase; protein kinase A; protein kinase A alpha; protein kinase A catalytic subunit; protein kinase cAMP-activated catalytic subunit alpha; protein kinase, cAMP dependent, catalytic, alpha; protein kinase, cAMP-dependent, alpha catalytic subunit; protein kinase, cAMP-dependent, catalytic, alpha; sperm cAMP-dependent protein kinase catalytic subunit; sperm cAMP-dependent protein kinase catalytic subunit Cs
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA