This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Acetyl-CoA Carboxylase Polyclonal Antibody
catalog :
PA5-17564
quantity :
100 uL
price :
US 514.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 4
Reference
Cai B, Ma M, Zhang J, Wang Z, Kong S, Zhou Z, et al. LncEDCH1 improves mitochondrial function to reduce muscle atrophy by interacting with SERCA2. Mol Ther Nucleic Acids. 2022;27:319-334 pubmed publisher
Wu Y, Chen F, Huang X, Zhang R, Yu Z, Chen Z, et al. Berberine (BBR) Attenuated Palmitic Acid (PA)-Induced Lipotoxicity in Human HK-2 Cells by Promoting Peroxisome Proliferator-Activated Receptor α (PPAR-α). Med Sci Monit. 2019;25:7702-7708 pubmed publisher
Gross A, Zimmermann A, Pendl T, Schroeder S, Schoenlechner H, Knittelfelder O, et al. Acetyl-CoA carboxylase 1-dependent lipogenesis promotes autophagy downstream of AMPK. J Biol Chem. 2019;294:12020-12039 pubmed publisher
Huang J, Zhou Y, Wan B, Wang Q, Wan X. Green tea polyphenols alter lipid metabolism in the livers of broiler chickens through increased phosphorylation of AMP-activated protein kinase. PLoS ONE. 2017;12:e0187061 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Acetyl-CoA Carboxylase Polyclonal Antibody
Catalog # :
PA5-17564
Quantity :
100 uL
Price :
US 514.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Bovine, Human, Mouse, Non-human primate, Rat
Applications :
Flow Cytometry: 1:50, Immunocytochemistry: 1:50, Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 1:50, Western Blot: 1:1,000
Species :
Bovine, Human, Mouse, Non-human primate, Rat
Isotype :
IgG
Storage :
-20 C
Description :
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Immunogen :
Synthetic peptide corresponding to residues surrounding Ser523 of human acetyl CoA carboxylase alpha1
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:50, Immunocytochemistry: 1:50, Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 1:50, Western Blot: 1:1,000
Aliases :
A1Z784_DROME; A530025K05Rik; Acac; Acaca; ACACAD; Acc; ACC1; ACCA; ACC-alpha; ACC-PA; ACC-PB; ACC-PC; ACC-PE; ACC-PF; ACC-PG; aceto-acetyl-CoA-thiolase; acetyl CoA carboxylase; acetyl coenzyme A carboxylase; Acetyl-CoA carboxylase; Acetyl-CoA carboxylase 1; acetyl-CoA carboxylase 265; acetyl-CoA carboxylase alpha; acetyl-CoA-carboxylase; acetyl-coenzyme A carboxylase; acetyl-coenzyme A carboxylase alpha; ACoT; Biotin carboxylase; CG11198; CG11198-PA; CG11198-PB; CG11198-PC; CG11198-PE; CG11198-PF; CG11198-PG; CG8723; dACC; DmACC; Dmel CG11198; Dmel_CG11198; EC 6.3.4.14; EC 6.4.1.2; FBgn0043811; GH12002p; Gm738; I79_006999; unnamed protein product
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA