PU.1 Polyclonal Antibody | Invitrogen PA5-17505 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PU.1 Polyclonal Antibody

catalog :

PA5-17505

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

citations: 9

Reference
Wu Z, Bai X, Lu Z, Liu S, Jiang H. LINC01094/SPI1/CCL7 Axis Promotes Macrophage Accumulation in Lung Adenocarcinoma and Tumor Cell Dissemination. J Immunol Res. 2022;2022:6450721 pubmed publisher
Wang L, Wang E, Prado Balcazar J, Wu Z, Xiang K, Wang Y, et al. Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis. Adv Sci (Weinh). 2021;:e2004673 pubmed publisher
Beguier F, Housset M, Roubeix C, Augustin S, Zagar Y, Nous C, et al. The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination. Immunity. 2020;53:429-441.e8 pubmed publisher
Knight A, Brill S, Solis C, Richardson M, McCarron M, Queen S, et al. Differential regulation of TREM2 and CSF1R in CNS macrophages in an SIV/macaque model of HIV CNS disease. J Neurovirol. 2020;26:511-519 pubmed publisher
Li T, Garcia Gomez A, Morante Palacios O, Ciudad L, Özkaramehmet S, Van Dijck E, et al. SIRT1/2 orchestrate acquisition of DNA methylation and loss of histone H3 activating marks to prevent premature activation of inflammatory genes in macrophages. Nucleic Acids Res. 2020;48:665-681 pubmed publisher
Soodgupta D, White L, Yang W, Johnston R, Andrews J, Kohyama M, et al. RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex. Cell Rep. 2019;29:829-843.e5 pubmed publisher
Faraoni I, Consalvo M, Aloisio F, Fabiani E, Giansanti M, Di Cristino F, et al. Cytotoxicity and Differentiating Effect of the Poly(ADP-Ribose) Polymerase Inhibitor Olaparib in Myelodysplastic Syndromes. Cancers (Basel). 2019;11: pubmed publisher
Ye B, Liu B, Yang L, Huang G, Hao L, Xia P, et al. Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2. Nat Commun. 2017;8:1518 pubmed publisher
Zheng S, Hedl M, Abraham C. TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages. J Immunol. 2015;194:1928-37 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PU.1 Polyclonal Antibody

Catalog # :

PA5-17505

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ChIP Assay: 1:25, Flow Cytometry: 1:50, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:400, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Synthetic peptide corresponding to amino acids at the amino-terminus of human PU.1

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 1:25, Flow Cytometry: 1:50, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:400, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Aliases :

31 kDa transforming protein; 31 kDa-transforming protein; 31kDa Transforming Protein; Dis1; Dis-1; hCG_25181; hematopoietic transcription factor PU.1; OF; Pu.1; SFFV proviral integration 1; SFFV proviral integration 1 protein; Sfpi1; Sfpi-1; Spi1; SPI-1; Spi-1 proto-oncogene; SPIA; SPI-A; spleen focus forming virus (SFFV) proviral integration oncogene; spleen focus forming virus (SFFV) proviral integration oncogene spi1; spleen focus forming virus proviral integration oncogene spi1; Tcfpu1; Tfpu.1; Transcription factor PU.1; Transcription Factor spi1