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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Caveolin 1 Polyclonal Antibody
catalog :
PA5-17447
quantity :
100 µL
price :
US 499.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
Chinese hamsters, human, mouse, rat, chicken, bovine, pigs , zebrafish
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 7a
Marinval N, Saboural P, Haddad O, Maire M, Bassand K, Geinguenaud F, et al. Identification of a Pro-Angiogenic Potential and Cellular Uptake Mechanism of a LMW Highly Sulfated Fraction of Fucoidan from Ascophyllum nodosum. Mar Drugs. 2016;14: pubmed
Rodrigues M, Gomes D, Fiorotto R, Guerra M, Weerachayaphorn J, Bo T, et al. Molecular determinants of peri-apical targeting of inositol 1,4,5-trisphosphate receptor type 3 in cholangiocytes. Hepatol Commun. 2022;6:2748-2764 pubmed publisher
Muranyi W, Schwerk C, Herold R, Stump Guthier C, Lampe M, Fallier Becker P, et al. Immortalized human choroid plexus endothelial cells enable an advanced endothelial-epithelial two-cell type in vitro model of the choroid plexus. iScience. 2022;25:104383 pubmed publisher
Simonneau C, Duschmal xe9 M, Gavrilov A, Brandenberg N, Hoehnel S, Ceroni C, et al. Investigating receptor-mediated antibody transcytosis using blood-brain barrier organoid arrays. Fluids Barriers CNS. 2021;18:43 pubmed publisher
Wang G, Hu Y, He M, Xie Y, Su W, Long D, et al. Gut-Lung Dysbiosis Accompanied by Diabetes Mellitus Leads to Pulmonary Fibrotic Change through the NF-κB Signaling Pathway. Am J Pathol. 2021;191:838-856 pubmed publisher
Lee H, Li C, Zhang Y, Zhang D, Otterbein L, Jin Y. Caveolin-1 selectively regulates microRNA sorting into microvesicles after noxious stimuli. J Exp Med. 2019;: pubmed publisher
product information
Product Type :
Antibody
Product Name :
Caveolin 1 Polyclonal Antibody
Catalog # :
PA5-17447
Quantity :
100 µL
Price :
US 499.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Bovine, Chicken, Hamster, Human, Mouse, Porcine, Rat, Zebrafish
Applications :
Flow Cytometry: 1:50, Immunocytochemistry: 1:400, Immunohistochemistry (Paraffin): 1:250, Immunoprecipitation: 1:50, Western Blot: 1:1,000
Species :
Bovine, Chicken, Hamster, Human, Mouse, Porcine, Rat, Zebrafish
Isotype :
IgG
Storage :
-20°C
Description :
Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.
Immunogen :
Synthetic peptide corresponding to residues surrounding Glu20 of human caveolin-1
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:50, Immunocytochemistry: 1:400, Immunohistochemistry (Paraffin): 1:250, Immunoprecipitation: 1:50, Western Blot: 1:1,000
Aliases :
BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA