Calcineurin A Polyclonal Antibody | Invitrogen PA5-17446 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Calcineurin A Polyclonal Antibody

catalog :

PA5-17446

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 3

Reference
Tuncay A, Noble A, Guille M, Cobley J. RedoxiFluor: A microplate technique to quantify target-specific protein thiol redox state in relative percentage and molar terms. Free Radic Biol Med. 2022;181:118-129 pubmed publisher
Song S, Park J, Jang S, Hwang E. Nicotinamide Treatment Facilitates Mitochondrial Fission through Drp1 Activation Mediated by SIRT1-Induced Changes in Cellular Levels of cAMP and Ca2. Cells. 2021;10: pubmed publisher
Davis R, Simon J, Utter M, Mungai P, Alvarez M, Chowdhury S, et al. Knockout of p21-activated kinase-1 attenuates exercise-induced cardiac remodelling through altered calcineurin signalling. Cardiovasc Res. 2015;108:335-47 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Calcineurin A Polyclonal Antibody

Catalog # :

PA5-17446

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Flow Cytometry: 1:25, Immunocytochemistry: 1:50, Immunoprecipitation: 1:50, Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

-20 C

Description :

Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.

Immunogen :

Synthetic peptide corresponding to the carboxy-terminus of human Calcineurin A (alpha isoform)

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:25, Immunocytochemistry: 1:50, Immunoprecipitation: 1:50, Western Blot: 1:1,000

Aliases :

2900074D19Rik; Ca2+/calmodulin-regulated protein phosphatase; calcineurin; calcineurin A alpha; Calcineurin A1; calcineurin catalytic subunit; calcineurin catalytic subunit delta isoform; Calcineurin subunit A alpha; CalcineurinA; calmodulin-dependent calcineurin A subunit alpha isoform; caln; CALNA; CALNA 1; CALNA1; CAM-PRP catalytic subunit; CCN 1; ccn1; CN; CnA; CNA alpha; CNA1; PP2B alpha 1; PP2BA alpha; PP2CB; ppp2b; ppp3ca; ppp3ca.S; protein phosphatase; protein phosphatase 2B, catalytic subunit, alpha isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha); protein phosphatase 3 catalytic subunit alpha; protein phosphatase 3 catalytic subunit alpha isozyme; protein phosphatase 3, catalytic subunit, alpha isoform; protein phosphatase 3, catalytic subunit, alpha isozyme; protein phosphatase 3, catalytic subunit, alpha isozyme S homeolog; protein phosphatase 3, catalytic subunit, gamma isozyme; protein phosphatase-2Ba; serine/threonine protein kinase; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; XELAEV_18009418mg