Profilin 1 Polyclonal Antibody | Invitrogen PA5-17444 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Profilin 1 Polyclonal Antibody

catalog :

PA5-17444

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunocytochemistry, flow cytometry

citations: 4

Reference
Cui S, Zhang T, Xiong X, Zhao J, Cao Q, Zhou H, et al. Detergent-insoluble PFN1 inoculation expedites disease onset and progression in PFN1 transgenic rats. Front Neurosci. 2023;17:1279259 pubmed publisher
Scotto di Carlo F, Russo S, Muyas F, Mangini M, Garribba L, Pazzaglia L, et al. Profilin 1 deficiency drives mitotic defects and reduces genome stability. Commun Biol. 2023;6:9 pubmed publisher
Scotto di Carlo F, Pazzaglia L, Esposito T, Gianfrancesco F. The Loss of Profilin 1 Causes Early Onset Paget's Disease of Bone. J Bone Miner Res. 2020;: pubmed publisher
Pinto Costa R, Sousa S, Leite S, Nogueira Rodrigues J, Ferreira da Silva T, Machado D, et al. Profilin 1 delivery tunes cytoskeletal dynamics toward CNS axon regeneration. J Clin Invest. 2020;130:2024-2040 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Profilin 1 Polyclonal Antibody

Catalog # :

PA5-17444

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Human, Mouse, Rat

Applications :

Flow Cytometry: 1:100, Immunocytochemistry: 1:50, Western Blot: 1:1,000

Species :

Bovine, Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role in both signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties but different expression patterns. Profilin I appears to be highly expressed in most tissues except for skeletal muscle. Profilin II is predominantly expressed in brain and at lower levels in skeletal muscle, uterus and kidney. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.

Immunogen :

Synthetic peptide corresponding to human profilin-1

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:100, Immunocytochemistry: 1:50, Western Blot: 1:1,000

Aliases :

actin binding protein; ALS18; Epididymis tissue protein Li 184a; Pfn; Pfn1; profilin 1; profilin I; Profilin-1