Phospho-NFkB p100 (Ser866, Ser870) Polyclonal Antibody | Invitrogen PA5-17385 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-NFkB p100 (Ser866, Ser870) Polyclonal Antibody

catalog :

PA5-17385

quantity :

100 uL

price :

US 460.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse

application :

western blot, immunoprecipitation

citations: 3

Reference
Zhao J, Geng W, Wan K, Guo K, Xi F, Xu X, et al. Lipoxin A4 promotes autophagy and inhibits overactivation of macrophage inflammasome activity induced by Pg LPS. J Int Med Res. 2021;49:300060520981259 pubmed publisher
Li L, Xia J, Cui R, Kong B. Solute carrier family 12 member 8 impacts the biological behaviors of breast carcinoma cells by activating TLR/NLR signaling pathway. Cytotechnology. 2021;73:23-34 pubmed publisher
Kopp S, Sahana J, Islam T, Petersen A, Bauer J, Corydon T, et al. The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine. Sci Rep. 2018;8:921 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-NFkB p100 (Ser866, Ser870) Polyclonal Antibody

Catalog # :

PA5-17385

Quantity :

100 uL

Price :

US 460.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunoprecipitation: 1:50, Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

Immunogen :

Synthetic phosphopeptide corresponding to residues surrounding serines 866/870 of NFkB2 p100 (homologous to pSer864/pSer868 of rat and pSer865/pSer869 of mouse)

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: 1:50, Western Blot: 1:1,000

Aliases :

CVID10; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; lyt; Lyt10; LYT-10; NF kappaB2; NF-kappaB2; NF-kB p100; NFKB, p52/p100 subunit; NFKB2; NF-kB2; nuclear factor kappa B subunit 2; nuclear factor Kappa-B, subunit 2; nuclear factor NF-kappa-B p100 subunit; Nuclear factor NF-kappa-B p52 subunit; nuclear factor of Kappa light chain gene enhancer in B cells 2; nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; oncogene Lyt-10; p100; p49; p49/p100; p50B; p52; RGD1307189; transcription factor NFKB2