alpha Actinin 1 Polyclonal Antibody | Invitrogen PA5-17308 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

alpha Actinin 1 Polyclonal Antibody

catalog :

PA5-17308

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Chinese hamsters, human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 5b	Latham S, Ehmke N, Reinke P, Taft M, Eicke D, Reindl T, et al. Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia. Nat Commun. 2018;9:4250 pubmed publisher
immunocytochemistry; human; fig 4 western blot; human; fig 3	Park S, Choi Y, Jung N, Yu Y, Ryu K, Kim H, et al. Myogenic differentiation potential of human tonsil-derived mesenchymal stem cells and their potential for use to promote skeletal muscle regeneration. Int J Mol Med. 2016;37:1209-20 pubmed publisher
	Wang C, Xie B, Yin S, Cao J, Huang J, Jin L, et al. Induction of filopodia formation by α-Actinin-2 via RelA with a feedforward activation loop promoting overt bone marrow metastasis of gastric cancer. J Transl Med. 2023;21:399 pubmed publisher
	Di Marco S, Carnicelli V, Franceschini N, Di Paolo M, Piccardi M, Bisti S, et al. Saffron: A Multitask Neuroprotective Agent for Retinal Degenerative Diseases. Antioxidants (Basel). 2019;8: pubmed publisher
	Tandon R, Brändl B, Baryshnikova N, Landshammer A, Steenpaß L, Keminer O, et al. Generation of two human isogenic iPSC lines from fetal dermal fibroblasts. Stem Cell Res. 2018;33:120-124 pubmed publisher
	Olgar Y, Durak A, Tuncay E, Bitirim C, Ozcinar E, Inan M, et al. Increased free Zn2+ correlates induction of sarco(endo)plasmic reticulum stress via altered expression levels of Zn2+ -transporters in heart failure. J Cell Mol Med. 2018;22:1944-1956 pubmed publisher
	Guan X, Wang Z, Czerniecki S, Mack D, François V, Blouin V, et al. Use of Adeno-Associated Virus to Enrich Cardiomyocytes Derived from Human Stem Cells. Hum Gene Ther Clin Dev. 2015;26:194-201 pubmed publisher

product information

Product Type :

Antibody

Product Name :

alpha Actinin 1 Polyclonal Antibody

Catalog # :

PA5-17308

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Hamster, Human, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 1:25, Western Blot: 1:1,000

Species :

Hamster, Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

-20 C

Description :

Alpha Actinin 1 belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Synthetic peptide corresponding to carboxy-terminal residues of human a-actinin-1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:25, Western Blot: 1:1,000

Aliases :

3110023F10Rik; actinin; actinin 1 smooth muscle; actinin alpha 1; actinin, alpha 1; Actn1; Actn1a; alpha actinin 1a; alpha-actinin; alpha-actinin cytoskeletal isoform; Alpha-actinin-1; BDPLT15; F-actin cross-linking protein; fibroblast alpha actinin; FLJ40884; FLJ54432; hypothetical protein; hypothetical protein LOC524770; I79_004057; non-muscle alpha-actinin 1; non-muscle alpha-actinin-1

more info or order :

Invitrogen product webpage