CDCP1 Polyclonal Antibody | Invitrogen PA5-17245 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CDCP1 Polyclonal Antibody

catalog :

PA5-17245

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; loading ...; fig 6a	Turdo F, Bianchi F, Gasparini P, Sandri M, Sasso M, De Cecco L, et al. CDCP1 is a novel marker of the most aggressive human triple-negative breast cancers. Oncotarget. 2016;7:69649-69665 pubmed publisher
	Forte L, Turdo F, Ghirelli C, Aiello P, Casalini P, Iorio M, et al. The PDGFRβ/ERK1/2 pathway regulates CDCP1 expression in triple-negative breast cancer. BMC Cancer. 2018;18:586 pubmed publisher
	Noskovičová N, Heinzelmann K, Burgstaller G, Behr J, Eickelberg O. Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation. Am J Physiol Lung Cell Mol Physiol. 2018;314:L695-L707 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CDCP1 Polyclonal Antibody

Catalog # :

PA5-17245

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Species :

Human

Isotype :

IgG

Storage :

-20 C

Description :

CDCP1 is a transmembrane protein containing three extracellular CUB domains. It is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. CDCP1 is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Immunogen :

Synthetic peptide corresponding to amino acids near the carboxy-terminus of human CDCP1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Aliases :

9030022E12Rik; AA409659; CD318; CDCP1; CUB domain containing protein 1; CUB domain-containing protein 1; E030027H19Rik; gp140; Membrane glycoprotein gp140; RGD1305578; SIMA135; Subtractive immunization M plus HEp3-associated 135 kDa protein; transmembrane and associated with src kinases; TRASK; UNQ2486/PRO5773

more info or order :

Invitrogen product webpage