WWOX Polyclonal Antibody | Invitrogen PA5-17237 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

WWOX Polyclonal Antibody

catalog :

PA5-17237

quantity :

100 uL

price :

US 404.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

citations: 1

Reference
Makii R, Cook H, Louke D, Breitbach J, Jennings R, Premanandan C, et al. Characterization of WWOX expression and function in canine mast cell tumors and malignant mast cell lines. BMC Vet Res. 2020;16:415 pubmed publisher

product information

Product Type :

Antibody

Product Name :

WWOX Polyclonal Antibody

Catalog # :

PA5-17237

Quantity :

100 uL

Price :

US 404.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

-20 C

Description :

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.

Immunogen :

Synthetic peptide corresponding to residues surrounding Thr103 of WWOX

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

5330426P09Rik; 9030416C10Rik; D16S432E; EIEE28; FOR; FRA16D; Fragile site FRA16D oxidoreductase; HHCMA56; PRO0128; SCAR12; SDR41C1; Short chain dehydrogenase/reductase family 41C member 1; short chain dehydrogenase/reductase family 41C, member 1; WOX1; WW domain containing oxidoreductase; WW domain-containing oxidoreductase; WW domain-containing protein WWOX; WW-domain oxidoreductase; Wwox