PBX1 Polyclonal Antibody | Invitrogen PA5-17223 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PBX1 Polyclonal Antibody

catalog :

PA5-17223

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 2

Reference
Zhang S, Weinberg S, DeBerge M, Gainullina A, Schipma M, Kinchen J, et al. Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair. Cell Metab. 2019;29:443-456.e5 pubmed publisher
Lu S, Zeumer L, Sorensen H, Yang H, Ng Y, Yu F, et al. The murine Pbx1-d lupus susceptibility allele accelerates mesenchymal stem cell differentiation and impairs their immunosuppressive function. J Immunol. 2015;194:43-55 pubmed

product information

Product Type :

Antibody

Product Name :

PBX1 Polyclonal Antibody

Catalog # :

PA5-17223

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ChIP Assay: 5 ug/10^6 cells, Immunocytochemistry: 1:400, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1; 19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Synthetic peptide corresponding to amino acids near the amino terminus of human Pbx1

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 5 ug/10^6 cells, Immunocytochemistry: 1:400, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Aliases :

2310056B04Rik; D230003C07Rik; DKFZp686B09108; Homeobox protein PBX1; homeobox protein PRL; MGC126627; OTTHUMP00000032205; PBX homeobox 1; Pbx1; Pbx-1; pre B cell leukemia homeobox 1; pre-B-cell leukemia homeobox 1; pre-B-cell leukemia transcription factor 1; PRL