ATG3 Polyclonal Antibody | Invitrogen PA5-17018 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ATG3 Polyclonal Antibody

catalog :

PA5-17018

quantity :

100 uL

price :

US 404.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, chicken, bovine, Xenopus laevis

application :

western blot

citations: 2

Reference
Sun J, Peng Y, Liu J, Zhou H, Sun L, He Q, et al. Pseudogene legumain promotes thyroid carcinoma progression via the microRNA-495/autophagy pathway. Oncol Lett. 2021;22:616 pubmed publisher
Vujić N, Bradić I, Goeritzer M, Kuentzel K, Rainer S, Kratky D, et al. ATG7 is dispensable for LC3-PE conjugation in thioglycolate-elicited mouse peritoneal macrophages. Autophagy. 2021;17:3402-3407 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ATG3 Polyclonal Antibody

Catalog # :

PA5-17018

Quantity :

100 uL

Price :

US 404.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Canine, Chicken, Human, Mouse, Non-human primate, Rat, Xenopus laevis

Applications :

Western Blot: 1:1,000

Species :

Bovine, Canine, Chicken, Human, Mouse, Non-human primate, Rat, Xenopus laevis

Isotype :

IgG

Storage :

-20 C

Description :

ATG3 (APG3) is a widely expressed conjugating enzyme for APG8 lipidation, an essential step for the initiation of autophagy. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. Autophagy is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG3 functions as an E2-like enzyme during the initial stages of autophagosome formation by catalyzing the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate, which is critical for autophagy.

Immunogen :

Synthetic peptide corresponding to residues near the amino terminus of Atg3

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

2610016C12Rik; APG3; Apg3l; APG3-like; Apg3p; atg3; ATG3 autophagy related 3 homolog; atg3.S; Atg3l; autophagy related 3; autophagy related 3 S homeolog; autophagy-related 3; autophagy-related protein 3; DKFZp564M1178; EGK_11288; FLJ22125; hApg3; MGC15201; PC3-96; Pig1; PIG-1; preconditioning-inducible gene 1 protein; Protein PC3-96; Ubiquitin-like-conjugating enzyme ATG3; XELAEV_18014721mg