VEGF Receptor 3 Polyclonal Antibody | Invitrogen PA5-16871 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

VEGF Receptor 3 Polyclonal Antibody

catalog :

PA5-16871

quantity :

500 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 4

Reference
Liu M, Huang J, Liu T, Yuan J, Lv C, Sha Z, et al. Exogenous interleukin 33 enhances the brain's lymphatic drainage and toxic protein clearance in acute traumatic brain injury mice. Acta Neuropathol Commun. 2023;11:61 pubmed publisher
Torres Ruiz S, Tormo E, Garrido Cano I, Lameirinhas A, Rojo F, Madoz G xfa rpide J, et al. High VEGFR3 Expression Reduces Doxorubicin Efficacy in Triple-Negative Breast Cancer. Int J Mol Sci. 2023;24: pubmed publisher
Hooks J, Bernard F, Cruz Acu xf1 a R, Nepiyushchikh Z, González Vargas Y, Garc xed a A, et al. Synthetic hydrogels engineered to promote collecting lymphatic vessel sprouting. Biomaterials. 2022;284:121483 pubmed publisher
Chadwick M, Lane A, Thomas D, Smith A, White A, Davidson D, et al. Combined mTOR and MEK inhibition is an effective therapy in a novel mouse model for angiosarcoma. Oncotarget. 2018;9:24750-24765 pubmed publisher

product information

Product Type :

Antibody

Product Name :

VEGF Receptor 3 Polyclonal Antibody

Catalog # :

PA5-16871

Quantity :

500 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Rat

Applications :

Immunocytochemistry: 1 ug/mL, Immunohistochemistry (Paraffin): 1:100, Western Blot: Assay-dependent

Species :

Human, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the development of theembryonic cardiovascular system before the emergence of the lymphatic vessels.

Immunogen :

A synthetic peptide derived from C-terminus of human Flt-4

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1 ug/mL, Immunohistochemistry (Paraffin): 1:100, Western Blot: Assay-dependent

Aliases :

AI323512; Chy; chylous ascites; Flt4; FLT-4; FLT41; fms related tyrosine kinase 4; FMS-like tyrosine kinase 4; fms-related tyrosine kinase 4; LMPH1A; PCL; receptor protein tyrosine kinase; soluble VEGFR 3; sVEGFR 3; tyrosine-protein kinase receptor FLT4; Vascular endothelial growth factor receptor 3; vascular endothelial growth factor receptor-3; VEGF R3; VEGFR3; VEGFR-3