This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
beta Tubulin Polyclonal Antibody
catalog :
PA5-16863
quantity :
500 uL
price :
US 478.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 17
Reference
Wang S, Chen J, Jiang Y, Lei Z, Ruan Y, Pan Y, et al. Targeting GSTP1 as Therapeutic Strategy against Lung Adenocarcinoma Stemness and Resistance to Tyrosine Kinase Inhibitors. Adv Sci (Weinh). 2023;10:e2205262 pubmed publisher
Wheatley B, Rey Suárez I, Hourwitz M, Kerr S, Shroff H, Fourkas J, et al. Nanotopography modulates cytoskeletal organization and dynamics during T cell activation. Mol Biol Cell. 2022;33:ar88 pubmed publisher
Merckx C, Cosemans G, Zschüntzsch J, Raedt R, Schmidt J, De Paepe B, et al. Description of Osmolyte Pathways in Maturing Mdx Mice Reveals Altered Levels of Taurine and Sodium/Myo-Inositol Co-Transporters. Int J Mol Sci. 2022;23: pubmed publisher
Stoneley M, Harvey R, Mulroney T, Mordue R, Jukes Jones R, Cain K, et al. Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress. Mol Cell. 2022;82:1557-1572.e7 pubmed publisher
Becker A, Wu P, Park J. eIF5A-Independent Role of DHPS in p21CIP1 and Cell Fate Regulation. Int J Mol Sci. 2021;22: pubmed publisher
Phan H, Kim N, Wei W, Tall G, Smrcka A. Uveal melanoma-associated mutations in PLCβ4 are constitutively activating and promote melanocyte proliferation and tumorigenesis. Sci Signal. 2021;14:eabj4243 pubmed publisher
Li W, Lin S, Chu C, Chang Y, Zhang X, Lin C, et al. The Gastroprotective Effect of Naringenin against Ethanol-Induced Gastric Ulcers in Mice through Inhibiting Oxidative and Inflammatory Responses. Int J Mol Sci. 2021;22: pubmed publisher
Yoon J, Cho L, Kim S, Tun W, Peng X, Pasriga R, et al. CTP synthase is essential for early endosperm development by regulating nuclei spacing. Plant Biotechnol J. 2021;19:2177-2191 pubmed publisher
Kui X, Wang Y, Zhang C, Li H, Li Q, Ke Y, et al. Prognostic value of SH3PXD2B (Tks4) in human hepatocellular carcinoma: a combined multi-omics and experimental study. BMC Med Genomics. 2021;14:115 pubmed publisher
Romer S, Metzger S, Peraza K, Wright M, Jobe D, Song L, et al. A mouse model of Huntington's disease shows altered ultrastructure of transverse tubules in skeletal muscle fibers. J Gen Physiol. 2021;153: pubmed publisher
Bodas M, Moore A, Subramaniyan B, Georgescu C, Wren J, Freeman W, et al. Cigarette Smoke Activates NOTCH3 to Promote Goblet Cell Differentiation in Human Airway Epithelial Cells. Am J Respir Cell Mol Biol. 2021;64:426-440 pubmed publisher
Yang C, Yang Y, Ma L, Zhang G, Shi F, Yan Y, et al. Study of the cytological features of bone marrow mesenchymal stem cells from patients with neuromyelitis optica. Int J Mol Med. 2019;43:1395-1405 pubmed publisher
Lillehoj E, Guang W, Hyun S, Liu A, Hegerle N, Simon R, et al. Neuraminidase 1-mediated desialylation of the mucin 1 ectodomain releases a decoy receptor that protects against Pseudomonas aeruginosa lung infection. J Biol Chem. 2019;294:662-678 pubmed publisher
Saldías M, Fernandez C, Morgan A, Díaz C, Morales D, Jaña F, et al. Aged blood factors decrease cellular responses associated with delayed gingival wound repair. PLoS ONE. 2017;12:e0184189 pubmed publisher
Urakov V, Mitkevich O, Safenkova I, Ter Avanesyan M. Ribosome-bound Pub1 modulates stop codon decoding during translation termination in yeast. FEBS J. 2017;284:1914-1930 pubmed publisher
Fokina A, Chechenova M, Karginov A, Ter Avanesyan M, Agaphonov M. Genetic Evidence for the Role of the Vacuole in Supplying Secretory Organelles with Ca2+ in Hansenula polymorpha. PLoS ONE. 2015;10:e0145915 pubmed publisher
Cottle D, Ursino G, Ip S, Jones L, DiTommaso T, Hacking D, et al. Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis. Hum Mol Genet. 2015;24:436-49 pubmed publisher
product information
Product Type :
Antibody
Product Name :
beta Tubulin Polyclonal Antibody
Catalog # :
PA5-16863
Quantity :
500 uL
Price :
US 478.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 1 ug/mL, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:1,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Beta-III tubulin is primarily expressed in neurons and may be involved in neurogenesis, axon guidance and maintenance. Mutations in the beta tubulin gene are the cause of congenital fibrosis of the extraocular muscles type 3. Beta-III tubulin was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues. Glutamate residues at the C-terminus of beta III tubulin can be glutamylated. The precise function of such modifications is unclear. Tubulin is phosphorylated on Ser-172 by CDK1 during cell cycle progression. Ser-172 phosphorylation inhibits tubulin incorporation into microtubules.Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55 kDa subunits: alpha and Beta. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. Because beta-tubulin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting.
Immunogen :
A synthetic peptide derived from aa 416-430 of human tubulin beta
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1 ug/mL, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:1,000
Aliases :
2310057H16Rik; 2810484G07Rik; 3200002H15Rik; AA408537; AI325297; AI596182; B130022C14Rik; bA631M21.2; BB220206; beta 5-tubulin; beta Ib tubulin; beta tubulin; beta tubulin 1; beta-4; beta-4 tubulin; beta-4-tubulin; beta-5; beta-5 tubulin; beta5-tubulin; betaIII-tubulin; beta-tubulin; beta-tubulin class-III; Beta-tubulin class-V; beta-tubulin class-VI; Beta-tubulin isotype I; c(beta)7 tubulin; CDCBM; CDCBM1; CDCBM5; CDCBM6; CFEOM3; CFEOM3A; class I beta tubulin; Class I beta-tubulin; class IIa beta-tubulin; class III beta-tubulin; class IVa beta-tubulin; class V beta tubulin; class V beta-tubulin; CSCSC1; dJ40E16.7; dystonia 4, torsion (autosomal dominant); DYT4; FEOM3; HSA10p15 beta-tubulin 4Q; HsT1601; hypothetical protein LOC540236; hypothetical protein LOC550458; I79_000194; I79_012097; LOC100349792; LOC100761889; LOW QUALITY PROTEIN: tubulin beta-6 chain; M(beta)1; M(beta)2; M(beta)3; M(beta)4; M(beta)5; M(beta)6; M40; M40 antibody; MGC128415 protein; MGC137802 protein; neuron-specific class III beta-tubulin; OK/SW-cl.56; OOMD; OOMD2; RGD1305887; si:ch211-122i22.4; si:ch211-9a18.2; Tubb; tubb beta-5; tubb.L; Tubb1; TUBB2; Tubb2a; tubb2a {ECO:0000250; Tubb3; TUBB4; TUBB4A; tubb5; TUBB-5; TUBB6; TUBB8; Tubulin 5 beta; tubulin beta; tubulin beta 1 class VI; tubulin beta 2A class IIa; tubulin beta 3 class III; tubulin beta 4'; tubulin beta 4A class IVa; tubulin beta 6 class V; tubulin beta 8 class VIII; Tubulin beta chain; tubulin beta class I; tubulin beta class I L homeolog; Tubulin beta class IIa; Tubulin beta class V; tubulin beta MGC4083; tubulin beta-1; tubulin beta-1 chain; tubulin beta-1 chain-like; tubulin beta-2A chain; tubulin beta-2B chain; tubulin beta-3 chain; Tubulin beta-4 chain; tubulin beta-4A chain; Tubulin beta-5 chain; tubulin beta-5 chain; tubulin beta-6 chain; tubulin beta-6 chain; Tubulin beta-7 chain; tubulin beta-8 chain; Tubulin beta-III; tubulin, beta 1 class VI; tubulin, beta 2; tubulin, beta 2A; tubulin, beta 2A class IIA; tubulin, beta 3; tubulin, beta 3 class III; tubulin, beta 4; tubulin, beta 4 class IVa; tubulin, beta 4A class IVa; tubulin, beta 5; tubulin, beta 5 class I; tubulin, beta 6 class V; tubulin, beta class I; tubulin, beta family 1; tubulin, beta polypeptide; tubulin, beta polypeptide 2; tubulin, beta, 3; tubulin, beta, 4; tubulin, beta, 5; uncharacterized protein LOC550458; UniProtKB:Q7TMM9}; Unknown (protein for MGC:134115); unnamed protein product; XELAEV_18039222mg; XLOT; zbetaI; zgc:112515
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA