This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Dystrophin Polyclonal Antibody
catalog :
PA5-16734
quantity :
500 µL
price :
US 436.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunohistochemistry - paraffin section
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; fig 1
Ryan T, Schmidt C, Green T, Spangenburg E, Neufer P, McClung J. Targeted Expression of Catalase to Mitochondria Protects Against Ischemic Myopathy in High-Fat Diet-Fed Mice. Diabetes. 2016;65:2553-68 pubmed publisher
Wellmann K, Kim J, Urso P, Smith Z, Johnson B. Evaluation of vitamin A status on myogenic gene expression and muscle fiber characteristics. J Anim Sci. 2021;99: pubmed publisher
Iyer S, Xu S, Shah S, Lovering R. Muscle phenotype of a rat model of Duchenne muscular dystrophy. Muscle Nerve. 2020;62:757-761 pubmed publisher
Klimczak A, Zimna A, Malcher A, Kozlowska U, Futoma K, Czarnota J, et al. Co-Transplantation of Bone Marrow-MSCs and Myogenic Stem/Progenitor Cells from Adult Donors Improves Muscle Function of Patients with Duchenne Muscular Dystrophy. Cells. 2020;9: pubmed publisher
Lee J. A Novel Mutation in N-Terminal Actin-Binding Domain of the DMD Gene Presenting Becker Muscular Dystrophy as Recurrent Exertional Rhabdomyolysis: A Case Report. Ann Indian Acad Neurol. 2020;23:123-125 pubmed publisher
Romero M, Mobley C, Mumford P, Roberson P, Haun C, Kephart W, et al. Acute and chronic resistance training downregulates select LINE-1 retrotransposon activity markers in human skeletal muscle. Am J Physiol Cell Physiol. 2018;314:C379-C388 pubmed publisher
Vulin A, Wein N, Simmons T, Rutherford A, Findlay A, Yurkoski J, et al. The first exon duplication mouse model of Duchenne muscular dystrophy: A tool for therapeutic development. Neuromuscul Disord. 2015;25:827-34 pubmed publisher
Pratt S, Shah S, Ward C, Kerr J, Stains J, Lovering R. Recovery of altered neuromuscular junction morphology and muscle function in mdx mice after injury. Cell Mol Life Sci. 2015;72:153-64 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Dystrophin Polyclonal Antibody
Catalog # :
PA5-16734
Quantity :
500 µL
Price :
US 436.00
Clonality :
Polyclonal
Purity :
purified
Host :
Rabbit
Reactivity :
Human, Rat
Applications :
Immunohistochemistry (Paraffin): 1:200-1:400
Species :
Human, Rat
Isotype :
IgG
Storage :
4° C
Description :
Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.
Immunogen :
A synthetic peptide corresponding to C-terminal of human Dystrophin
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:200-1:400
Aliases :
apodystrophin-3; apodystrophin-I; BMD; CMD3B; dmd; dmd.1; dmd.1.L; DNADMD1; Dp427; Dp71; Duchenne muscular dystrophy (DMD); DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; DXSmh7; DXSmh9; dys; Dystrophin; dystrophin Dp40; dystrophin Dp71 isoform; dystrophin Dp71a; dystrophin Dp71ab; dystrophin Dp71b; dystrophin, gene 1 L homeolog; dystrophin, muscular dystrophy; GS1-19O24.1; mdx; MRX85; Muscular dystrophy Duchenne and Becker types; OTTHUMP00000215592; pke; utrn; utrophin; XELAEV_18012903mg; X-linked muscular dystrophy
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA