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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cytokeratin 14 Polyclonal Antibody
catalog :
PA5-16722
quantity :
500 uL
price :
US 460.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, mass cytometry
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 6k
Ni N, Fang X, Li Q. Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract. Sci Rep. 2021;11:9294 pubmed publisher
  • mass cytometry; human; loading ...; fig 3a
Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 7a
Gesteira T, Sun M, Coulson Thomas Y, Yamaguchi Y, Yeh L, Hascall V, et al. Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation. Invest Ophthalmol Vis Sci. 2017;58:4407-4421 pubmed publisher
  • immunocytochemistry; mouse; 1:500
  • immunocytochemistry; human; 1:4000; loading ...; fig 1c, ED1g
  • western blot; human; 1:2000; loading ...; fig 2c, ED4b
Britschgi A, Duss S, Kim S, Couto J, Brinkhaus H, Koren S, et al. The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα. Nature. 2017;541:541-545 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1b
Sheen M, Marotti J, Allegrezza M, Rutkowski M, Conejo Garcia J, Fiering S. Constitutively activated PI3K accelerates tumor initiation and modifies histopathology of breast cancer. Oncogenesis. 2016;5:e267 pubmed publisher
Wang W, Spurgeon M, Pope A, McGregor S, Ward Shaw E, Gronski E, et al. Stress keratin 17 and estrogen support viral persistence and modulate the immune environment during cervicovaginal murine papillomavirus infection. Proc Natl Acad Sci U S A. 2023;120:e2214225120 pubmed publisher
Obr A, Bulatowicz J, Chang Y, Ciliento V, Lemenze A, Maingrette K, et al. Breast tumor IGF1R regulates cell adhesion and metastasis: alignment of mouse single cell and human breast cancer transcriptomics. Front Oncol. 2022;12:990398 pubmed publisher
Ni N, Jalufka F, Fang X, McCreedy D, Li Q. Role of EZH2 in Uterine Gland Development. Int J Mol Sci. 2022;23: pubmed publisher
Schreiner T, Allnoch L, Beythien G, Marek K, Becker K, Schaudien D, et al. SARS-CoV-2 Infection Dysregulates Cilia and Basal Cell Homeostasis in the Respiratory Epithelium of Hamsters. Int J Mol Sci. 2022;23: pubmed publisher
Fang X, Ni N, Wang X, Tian Y, Ivanov I, Rijnkels M, et al. EZH2 and Endometrial Cancer Development: Insights from a Mouse Model. Cells. 2022;11: pubmed publisher
Wang W, Uberoi A, Spurgeon M, Gronski E, Majerciak V, Lobanov A, et al. Stress keratin 17 enhances papillomavirus infection-induced disease by downregulating T cell recruitment. PLoS Pathog. 2020;16:e1008206 pubmed publisher
Fang X, Ni N, Lydon J, Ivanov I, Bayless K, Rijnkels M, et al. Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit Is Required for Uterine Epithelial Integrity. Am J Pathol. 2019;189:1212-1225 pubmed publisher
Jokela T, Engelsen A, Rybicka A, Pelissier Vatter F, Garbe J, Miyano M, et al. Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance. Front Cell Dev Biol. 2018;6:41 pubmed publisher
Schulz D, Zanotelli V, Fischer J, Schapiro D, Engler S, Lun X, et al. Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry. Cell Syst. 2018;6:25-36.e5 pubmed publisher
Todhunter M, Jee N, Hughes A, Coyle M, Cerchiari A, Farlow J, et al. Programmed synthesis of three-dimensional tissues. Nat Methods. 2015;12:975-81 pubmed publisher
Koren S, Reavie L, Couto J, De Silva D, Stadler M, Roloff T, et al. PIK3CA(H1047R) induces multipotency and multi-lineage mammary tumours. Nature. 2015;525:114-8 pubmed publisher
Hines W, Yaswen P, Bissell M. Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias. Nat Commun. 2015;6:6927 pubmed publisher
Maity G, De A, Das A, Banerjee S, Sarkar S, Banerjee S. Aspirin blocks growth of breast tumor cells and tumor-initiating cells and induces reprogramming factors of mesenchymal to epithelial transition. Lab Invest. 2015;95:702-17 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Cytokeratin 14 Polyclonal Antibody
Catalog # :
PA5-16722
Quantity :
500 uL
Price :
US 460.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunohistochemistry (Paraffin): 1:200, Western Blot: 1 ug/mL
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
Immunogen :
A synthetic peptide derived from C-terminal of human Keratin 14
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:200, Western Blot: 1 ug/mL
Aliases :
AI626930; CK14; CK-14; cytokeratin 14; cytokeratin-14; EBS3; EBS4; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; Ka14; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; keratin, type I cytoskeletal 14; keratin, type I cytoskeletal 17; keratin-14; Koebner; Krt-1.14; Krt1-14; KRT14; LOC100737113; NFJ; Type I keratin Ka14
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA