AFP Polyclonal Antibody | Invitrogen PA5-16658 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

AFP Polyclonal Antibody

catalog :

PA5-16658

quantity :

500 µL

price :

US 239.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, pigs , domestic sheep

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 3

Reference
Zhao Y, Li Z, Zhu Y, Fu J, Zhao X, Zhang Y, et al. Single-Cell Transcriptome Analysis Uncovers Intratumoral Heterogeneity and Underlying Mechanisms for Drug Resistance in Hepatobiliary Tumor Organoids. Adv Sci (Weinh). 2021;8:e2003897 pubmed publisher
Artegiani B, Hendriks D, Beumer J, Kok R, Zheng X, Joore I, et al. Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing. Nat Cell Biol. 2020;22:321-331 pubmed publisher
Morrison G, Scognamiglio R, Trumpp A, Smith A. Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification. EMBO J. 2016;35:356-68 pubmed publisher

product information

Product Type :

Antibody

Product Name :

AFP Polyclonal Antibody

Catalog # :

PA5-16658

Quantity :

500 µL

Price :

US 239.00

Clonality :

Polyclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Human, Ovine, Porcine

Applications :

Immunocytochemistry: 1:100-1:250, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:250-1:1,000

Species :

Human, Ovine, Porcine

Isotype :

IgG

Storage :

4° C

Description :

AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.

Immunogen :

Purified alpha-fetoprotein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:250, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:250-1:1,000

Aliases :

a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein