PDGFRA Polyclonal Antibody | Invitrogen PA5-16571 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PDGFRA Polyclonal Antibody

catalog :

PA5-16571

quantity :

500 µL

price :

US 440.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; loading ...; fig 1a	Velasco Estevez M, Koch N, Klejbor I, Laurent S, Dev K, Szutowicz A, et al. EBI2 Is Temporarily Upregulated in MO3.13 Oligodendrocytes during Maturation and Regulates Remyelination in the Organotypic Cerebellar Slice Model. Int J Mol Sci. 2021;22: pubmed publisher
	Toomey L, Papini M, Clarke T, Wright A, Denham E, Warnock A, et al. Secondary Degeneration of Oligodendrocyte Precursor Cells Occurs as Early as 24 h after Optic Nerve Injury in Rats. Int J Mol Sci. 2023;24: pubmed publisher
	Velasco Estevez M, Koch N, Klejbor I, Caratis F, Rutkowska A. Mechanoreceptor Piezo1 Is Downregulated in Multiple Sclerosis Brain and Is Involved in the Maturation and Migration of Oligodendrocytes in vitro. Front Cell Neurosci. 2022;16:914985 pubmed publisher
	Taglietti V, Kefi K, Bronisz Budzy x144 ska I, Mirciloglu B, Rodrigues M, Cardone N, et al. Duchenne muscular dystrophy trajectory in R-DMDdel52 preclinical rat model identifies COMP as biomarker of fibrosis. Acta Neuropathol Commun. 2022;10:60 pubmed publisher
	Li B, Qiao C, Jin X, Chan H. Characterizing the Low-Dose Effects of Methylmercury on the Early Stages of Embryo Development Using Cultured Human Embryonic Stem Cells. Environ Health Perspect. 2021;129:77007 pubmed publisher
	Agha O, Mueller Immergluck A, Liu M, Zhang H, Theologis A, Clark A, et al. Intervertebral disc herniation effects on multifidus muscle composition and resident stem cell populations. JOR Spine. 2020;3:e1091 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PDGFRA Polyclonal Antibody

Catalog # :

PA5-16571

Quantity :

500 µL

Price :

US 440.00

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 2 µg/mL, Immunohistochemistry: Assay-dependent, Western Blot: 1-3 µg/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

4° C

Description :

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

Immunogen :

A synthetic peptide derived from the C-terminus of the precursor form of human PDGFR, alpha

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 µg/mL, Immunohistochemistry: Assay-dependent, Western Blot: 1-3 µg/mL

Aliases :

AI115593; alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; APDGFR; CD140 antigen-like family member A; CD140A; CD140a antigen; GAS9; MGC74795; OTTHUMP00000218656; PDGF A-chain; PDGF alpha chain; PDGF Receptor alpha; PDGF subunit A; PDGF-1; PDGFACE; PDGFR2; Pdgfr-2; PDGFRA; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; platelet derived growth factor receptor alpha; platelet derived growth factor receptor, alpha polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA