NFkB p65 Polyclonal Antibody | Invitrogen PA5-16545 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NFkB p65 Polyclonal Antibody

catalog :

PA5-16545

quantity :

500 uL

price :

US 506.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Chinese hamsters, human, mouse, rat, dogs, bovine, pigs , Xenopus laevis

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 24

Reference
Aoki Y, Dai H, Furuta F, Akamatsu T, Oshima T, Takahashi N, et al. LOX-1 mediates inflammatory activation of microglial cells through the p38-MAPK/NF-κB pathways under hypoxic-ischemic conditions. Cell Commun Signal. 2023;21:126 pubmed publisher
Peng P, Wang D, Xu X, Wang D, Gao B, Wang H, et al. Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration. Arthritis Res Ther. 2022;24:181 pubmed publisher
Liu X, Wang M, Song Y, Zhang C, Jiang Y, Li W, et al. Kukoamine A inhibits C-C motif chemokine receptor 5 to attenuate lipopolysaccharide-induced lung injury. Drug Dev Res. 2022;83:1455-1466 pubmed publisher
Barakat R, Campbell C, Espin Palazon R. Identification of Transcription Factor Binding Sites by Cleavage Under Target and Release Using Nuclease in Zebrafish. Zebrafish. 2022;19:104-108 pubmed publisher
El Sherbiny M, El Shafey M, Said E, Shaker G, El Dosoky M, Ebrahim H, et al. Dapagliflozin, Liraglutide, and Their Combination Attenuate Diabetes Mellitus-Associated Hepato-Renal Injury-Insight into Oxidative Injury/Inflammation/Apoptosis Modulation. Life (Basel). 2022;12: pubmed publisher
Abdelrahman R, Abdelsalam R, Zaghloul M. Beneficial effect of trimetazidine on folic acid-induced acute kidney injury in mice: Role of HIF-1α/HO-1. J Biochem Mol Toxicol. 2022;36:e23011 pubmed publisher
Zhang Y, Zhang H, Sun X, Peng T, Xie T, Yuan Y, et al. Nucleic acid aptamer controls mycoplasma infection for inhibiting the malignancy of esophageal squamous cell carcinoma. Mol Ther. 2022;30:2224-2241 pubmed publisher
Kirchhoff K, Billion A, Voolstra C, Kremb S, Wilke T, Vilcinskas A. Stingray Venom Proteins: Mechanisms of Action Revealed Using a Novel Network Pharmacology Approach. Mar Drugs. 2021;20: pubmed publisher
Bishop T, Beck C. Bacterial lipopolysaccharides can initiate regeneration of the Xenopus tadpole tail. iScience. 2021;24:103281 pubmed publisher
Zhao X, Dong B, Friesen M, Liu S, Zhu C, Yang C. Capsaicin Attenuates Lipopolysaccharide-Induced Inflammation and Barrier Dysfunction in Intestinal Porcine Epithelial Cell Line-J2. Front Physiol. 2021;12:715469 pubmed publisher
Chade A, Engel J, Hall M, Eirin A, Bidwell G. Intrarenal modulation of NF-κB activity attenuates cardiac injury in a swine model of CKD: a renal-cardio axis. Am J Physiol Renal Physiol. 2021;321:F411-F423 pubmed publisher
Jiang H, Zhou Y, Zhou P, Zhang T, Hu J, Bai X. Protective Effects of Bariatric Surgery on Kidney Functions by Inhibiting Oxidative Stress Responses Through Activating PPARα in Rats With Diabetes. Front Physiol. 2021;12:662666 pubmed publisher
Song M, Lee S, Kim M, Park S, Park J, Kwon Y, et al. Saururus chinensis-controlled allergic pulmonary disease through NF-κB/COX-2 and PGE2 pathways. Peerj. 2020;8:e10043 pubmed publisher
Ullah M, Liu D, Rai S, Razavi M, Concepcion W, Thakor A. Pulsed focused ultrasound enhances the therapeutic effect of mesenchymal stromal cell-derived extracellular vesicles in acute kidney injury. Stem Cell Res Ther. 2020;11:398 pubmed publisher
Zhang X, Liu S, Zhu Y. A-kinase-interacting protein 1 promotes EMT and metastasis via PI3K/Akt/IKKβ pathway in cervical cancer. Cell Biochem Funct. 2020;38:782-791 pubmed publisher
Lee S, Cho S, Li Y, Bae C, Park K, Park D. Anti-inflammatory Effect of Curcuma longa and Allium hookeri Co-treatment via NF-κB and COX-2 Pathways. Sci Rep. 2020;10:5718 pubmed publisher
Maekawa H, Inoue T, Ouchi H, Jao T, Inoue R, Nishi H, et al. Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury. Cell Rep. 2019;29:1261-1273.e6 pubmed publisher
Rojas Morales P, Tapia E, León Contreras J, González Reyes S, Jiménez Osorio A, Trujillo J, et al. Mechanisms of Fasting-Mediated Protection against Renal Injury and Fibrosis Development after Ischemic Acute Kidney Injury. Biomolecules. 2019;9: pubmed publisher
Guo G, Tian A, Lan X, Fu C, Yan Z, Wang C. Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway. Exp Ther Med. 2019;17:4080-4088 pubmed publisher
Dahiya S, Onteru S, Singh D. Inhibition of indoleamine 2,3-dioxygenase attenuates endotoxin-mediated tolerance in granulosa cells through kynurenine pathway. J Cell Biochem. 2019;120:11931-11940 pubmed publisher
el Agamy D, El Harbi K, Khoshhal S, Ahmed N, Elkablawy M, Shaaban A, et al. Pristimerin protects against doxorubicin-induced cardiotoxicity and fibrosis through modulation of Nrf2 and MAPK/NF-kB signaling pathways. Cancer Manag Res. 2019;11:47-61 pubmed publisher
Aratani S, Tagawa M, Nagasaka S, Sakai Y, Shimizu A, Tsuruoka S. Radiation-induced premature cellular senescence involved in glomerular diseases in rats. Sci Rep. 2018;8:16812 pubmed publisher
Sekkien A, Swilam N, Ebada S, Esmat A, El Khatib A, Linscheid M, et al. Polyphenols from Tamarix nilotica: LC⁻ESI-MSn Profiling and In Vivo Antifibrotic Activity. Molecules. 2018;23: pubmed publisher
Zhang K, Xu P, Sowers J, Machuca D, Mirfattah B, Herring J, et al. Proteome Analysis of Hypoxic Glioblastoma Cells Reveals Sequential Metabolic Adaptation of One-Carbon Metabolic Pathways. Mol Cell Proteomics. 2017;16:1906-1921 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NFkB p65 Polyclonal Antibody

Catalog # :

PA5-16545

Quantity :

500 uL

Price :

US 506.00

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Bovine, Canine, Drosophila, Hamster, Human, Mouse, Porcine, Rabbit, Rat, Xenopus laevis

Applications :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 5-10 ug/mL

Species :

Bovine, Canine, Drosophila, Hamster, Human, Mouse, Porcine, Rabbit, Rat, Xenopus laevis

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.

Immunogen :

A synthetic peptide from the C-terminus of human NFkappaB protein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 5-10 ug/mL

Aliases :

avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela