This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PARP1 Polyclonal Antibody
catalog :
PA5-16452
quantity :
500 µL
price :
US 504
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; fig 6
Ware M, Colbert K, Keshishian V, Ho J, Corr S, Curley S, et al. Generation of Homogenous Three-Dimensional Pancreatic Cancer Cell Spheroids Using an Improved Hanging Drop Technique. Tissue Eng Part C Methods. 2016;22:312-21 pubmed publisher
Guru N, Dem xe9 trio de Souza Fran xe7 a P, Pirovano G, Huang C, Patel S, Reiner T. [18F]PARPi Imaging Is Not Affected by HPV Status In Vitro. Mol Imaging. 2021;2021:6641397 pubmed publisher
Rajendran P, Ammar R, Al Saeedi F, Mohamed M, ElNaggar M, Al ramadan S, et al. Kaempferol Inhibits Zearalenone-Induced Oxidative Stress and Apoptosis via the PI3K/Akt-Mediated Nrf2 Signaling Pathway: In Vitro and In Vivo Studies. Int J Mol Sci. 2020;22: pubmed publisher
Wilson T, Jannetti S, Guru N, Pillarsetty N, Reiner T, Pirovano G. Improved radiosynthesis of 123I-MAPi, an auger theranostic agent. Int J Radiat Biol. 2020;:1-7 pubmed publisher
Kossatz S, Pirovano G, Demétrio De Souza França P, Strome A, Sunny S, Zanoni D, et al. Validation of the use of a fluorescent PARP1 inhibitor for the detection of oral, oropharyngeal and oesophageal epithelial cancers. Nat Biomed Eng. 2020;4:272-285 pubmed publisher
Pirovano G, Jannetti S, Carter L, Sadique A, Kossatz S, Guru N, et al. Targeted Brain Tumor Radiotherapy Using an Auger Emitter. Clin Cancer Res. 2020;26:2871-2881 pubmed publisher
product information
Product Type :
Antibody
Product Name :
PARP1 Polyclonal Antibody
Catalog # :
PA5-16452
Quantity :
500 µL
Price :
US 504
Clonality :
Polyclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1 µg/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
4° C
Description :
Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.
Immunogen :
A synthetic peptide for the N-terminal region of human PARP
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1 µg/mL
Aliases :
5830444G22Rik; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); Adprp; Adprt; ADPRT 1; Adprt1; AI893648; ARTD1; C80510; DNA ADP-ribosyltransferase PARP1; I79_014850; msPARP; NAD(+) ADP-ribosyltransferase 1; NAD(+) pADPRT-1; pADPRT-1; PARP; PARP1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); poly [ADP-ribose] polymerase 1; poly ADP-ribose polymerase; poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase 1; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; Poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; Protein poly-ADP-ribosyltransferase PARP1; sPARP-1; synthetase fragment (AA 67); Unknown (protein for IMAGE:8023736); unnamed protein product
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA