Hepatitis B Virus Core Antigen Polyclonal Antibody | Invitrogen PA5-16368 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Hepatitis B Virus Core Antigen Polyclonal Antibody

catalog :

PA5-16368

quantity :

500µL

price :

US 249.00

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

Hepatitis B virus

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; Hepatitis B virus	Cheng P, Tsai H, Chiu Y, Ho C, Wu I, Chang T. Clinical significance of serum HBsAg levels and association with liver histology in HBeAg positive chronic hepatitis B. J Clin Virol. 2013;57:323-30 pubmed publisher
immunohistochemistry; Hepatitis B virus	Dai J, Chen E, Bai L, Gong D, Zhou Q, Cheng X, et al. Biological characteristics of the rtA181T/sW172* mutant strain of Hepatitis B virus in animal model. Virol J. 2012;9:280 pubmed publisher
immunohistochemistry; Hepatitis B virus; 1:200	He F, Chen E, Liu L, Zhou T, Liu C, Cheng X, et al. Inhibition of hepatitis B Virus replication by hepatocyte nuclear factor 4-alpha specific short hairpin RNA. Liver Int. 2012;32:742-51 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Hepatitis B Virus Core Antigen Polyclonal Antibody

Catalog # :

PA5-16368

Quantity :

500µL

Price :

US 249.00

Clonality :

Polyclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Virus

Applications :

Immunohistochemistry (Paraffin): 1:100-1:200

Species :

Virus

Isotype :

IgG

Storage :

4° C

Description :

The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. Hepatitis B virus is spherical in shape with a diameter of 42nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.

Immunogen :

Hepatitis B virus

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:100-1:200

Aliases :

HepB; Hepatitis B virus nucleocapsid particles; HBcAg