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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD31 Polyclonal Antibody
catalog :
PA5-16301
quantity :
500 uL
price :
US 514.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 26
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; fig 5
Huang Y, Lan Q, Ponsonnet L, Blanquet M, Christofori G, Zaric J, et al. The matricellular protein CYR61 interferes with normal pancreatic islets architecture and promotes pancreatic neuroendocrine tumor progression. Oncotarget. 2016;7:1663-74 pubmed publisher
  • immunocytochemistry; human; 1:25; fig 2
Stebbins M, Wilson H, Canfield S, Qian T, Palecek S, Shusta E. Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells. Methods. 2016;101:93-102 pubmed publisher
Mandakhbayar N, Ji Y, El Fiqi A, Patel K, Yoon D, Dashnyam K, et al. Double hits with bioactive nanozyme based on cobalt-doped nanoglass for acute and diabetic wound therapies through anti-inflammatory and pro-angiogenic functions. Bioact Mater. 2024;31:298-311 pubmed publisher
Russell T, Dirar Q, Li Y, Chiang C, Laskowitz D, Yun Y. Cortical spheroid on perfusable microvascular network in a microfluidic device. PLoS ONE. 2023;18:e0288025 pubmed publisher
Drza x142 A, Dziurman G, Ho x142 a P, Lechowski J, Delalande A, Swako x144 J, et al. Murine Breast Cancer Radiosensitization Using Oxygen Microbubbles and Metformin: Vessels Are the Key. Int J Mol Sci. 2023;24: pubmed publisher
Khurana N, Babajanian E, McCrary H, Pulsipher A, Ghandehari H, Alt J, et al. Vascular permeability in HPV+ oropharyngeal cancers aids in fluorescent image-guided transoral robotic surgery using indocyanine green. Head Neck. 2023;45:1728-1740 pubmed publisher
Mamana J, Humber G, Espinal E, Seo S, Vollmuth N, Sin J, et al. Coxsackievirus B3 infects and disrupts human induced-pluripotent stem cell derived brain-like endothelial cells. Front Cell Infect Microbiol. 2023;13:1171275 pubmed publisher
Belhoul Fakir H, Wu J, Yeow Y, Musk G, Kershaw H, Ingley E, et al. Injury to the tunica media initiates atherogenesis in the presence of hyperlipidemia. Front Cardiovasc Med. 2023;10:1152124 pubmed publisher
Lin Y, Lee S, Cheng Y. Low-Level Laser Therapy Induces Melanoma Tumor Growth by Promoting Angiogenesis. Life (Basel). 2023;13: pubmed publisher
C xe1 rdenas Calder xf3 n C, Veloso Gim xe9 nez V, Gonz xe1 lez T, Wozniak A, Garc xed a P, Mart xed n S, et al. Development of an implantable three-dimensional model of a functional pathogenic multispecies biofilm to study infected wounds. Sci Rep. 2022;12:21846 pubmed publisher
Schaal J, Bhattacharyya J, Brownstein J, Strickland K, Kelly G, Saha S, et al. Brachytherapy via a depot of biopolymer-bound 131I synergizes with nanoparticle paclitaxel in therapy-resistant pancreatic tumours. Nat Biomed Eng. 2022;6:1148-1166 pubmed publisher
Casas B, Vit xf3 ria G, Prieto C, Casas M, Chac xf3 n C, Uhrig M, et al. Schizophrenia-derived hiPSC brain microvascular endothelial-like cells show impairments in angiogenesis and blood-brain barrier function. Mol Psychiatry. 2022;27:3708-3718 pubmed publisher
Malolina E, Galiakberova A, Dashinimaev E, Kulibin A. Establishment of a pure culture of immature Sertoli cells by PDGFRA staining and cell sorting. Mol Reprod Dev. 2022;89:243-255 pubmed publisher
Man A, Zhou Y, Lam U, Reifenberg G, Werner A, Habermeier A, et al. l-Citrulline ameliorates pathophysiology in a rat model of superimposed preeclampsia. Br J Pharmacol. 2022;179:3007-3023 pubmed publisher
Yao M, Lu Y, Shi L, Huang Y, Zhang Q, Tan J, et al. A ROS-responsive, self-immolative and self-reporting hydrogen sulfide donor with multiple biological activities for the treatment of myocardial infarction. Bioact Mater. 2022;9:168-182 pubmed publisher
Kim S, Moon G, Kim H, Kim D, Kim J, Nam Y, et al. Control of hippocampal prothrombin kringle-2 (pKr-2) expression reduces neurotoxic symptoms in five familial Alzheimer's disease mice. Br J Pharmacol. 2022;179:998-1016 pubmed publisher
Bruno M, Mukherjee S, Stromberg A, Saito H, Starr M. Visceral fat-specific regulation of plasminogen activator inhibitor-1 in aged septic mice. J Cell Physiol. 2022;237:706-719 pubmed publisher
Ou Y, Clifton B, Li J, Sandlin D, Li N, Wu L, et al. Traumatic brain injury induced by exposure to blast overpressure via ear canal. Neural Regen Res. 2022;17:115-121 pubmed publisher
Li L, Yang Y, Zhang H, Du Y, Jiao X, Yu H, et al. Salidroside Ameliorated Intermittent Hypoxia-Aggravated Endothelial Barrier Disruption and Atherosclerosis via the cAMP/PKA/RhoA Signaling Pathway. Front Pharmacol. 2021;12:723922 pubmed publisher
Jung E, Osswald M, Ratliff M, Dogan H, Xie R, Weil S, et al. Tumor cell plasticity, heterogeneity, and resistance in crucial microenvironmental niches in glioma. Nat Commun. 2021;12:1014 pubmed publisher
Khurana N, Pulsipher A, Jedrzkiewicz J, Ashby S, Pollard C, Ghandehari H, et al. Inflammation-driven vascular dysregulation in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2021;11:976-983 pubmed publisher
Sun X, Xiao L, Chen J, Chen X, Chen X, Yao S, et al. DNA methylation is involved in the pathogenesis of osteoarthritis by regulating CtBP expression and CtBP-mediated signaling. Int J Biol Sci. 2020;16:994-1009 pubmed publisher
Ramamoorthy P, Thomas S, Kaushik G, Subramaniam D, Chastain K, Dhar A, et al. Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response. Cancer Res. 2019;79:1681-1695 pubmed publisher
Huyut Z, Bakan N, Yildirim S, Alp H. Effects of the Phosphodiesterase-5 (PDE-5) Inhibitors, Avanafil and Zaprinast, on Bone Remodeling and Oxidative Damage in a Rat Model of Glucocorticoid-Induced Osteoporosis. Med Sci Monit Basic Res. 2018;24:47-58 pubmed publisher
Alp H, Huyut Z, Yildirim S, Basbugan Y, Ediz L, Sekeroğlu M. The effect of PDE5 inhibitors on bone and oxidative damage in ovariectomy-induced osteoporosis. Exp Biol Med (Maywood). 2017;242:1051-1061 pubmed publisher
de Wispelaere M, Frenkiel M, Desprès P. A Japanese encephalitis virus genotype 5 molecular clone is highly neuropathogenic in a mouse model: impact of the structural protein region on virulence. J Virol. 2015;89:5862-75 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD31 Polyclonal Antibody
Catalog # :
PA5-16301
Quantity :
500 uL
Price :
US 514.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:500
Species :
Human
Isotype :
IgG
Storage :
4 C
Description :
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
Immunogen :
Synthetic peptide corresponding to mouse CD31, aa 700 to the C-terminus.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:500
Aliases :
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA