Cyclin C Polyclonal Antibody | Invitrogen PA5-16227 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cyclin C Polyclonal Antibody

catalog :

PA5-16227

quantity :

500µL

price :

425.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 1

Reference
Ganesan V, Willis S, Chang K, Beluch S, Cooper K, Strich R. Cyclin C directly stimulates Drp1 GTP affinity to mediate stress-induced mitochondrial hyperfission. Mol Biol Cell. 2019;30:302-311 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cyclin C Polyclonal Antibody

Catalog # :

PA5-16227

Quantity :

500µL

Price (USD) :

425.00 USD

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Canine, Human, Mouse, Rat

Applications :

Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 10 µg/mg protein lysate, Western Blot: 2 µg/mL

Species :

Canine, Human, Mouse, Rat

Isotype :

IgG

Storage :

4° C

Description :

Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knock out of the CLN genes in Saccharomyces cerevisiae. Cyclin C is a nuclear protein present in a multiprotein complex. It interacts both in vitro and in vivo with cdk 8, a novel protein kinase of the cdk family. It is suggested that cyclin C and cdk 8 control RNA polymerase II function. Human cdk 8 cyclin C might be functionally associated with the mammalian transcription apparatus, perhaps involved in relaying growth regulatory signals.

Immunogen :

A synthetic peptide corresponding to aa 290-303 (Cys-QGPNGSQNSSYSQS) from the C-terminal of human cyclin C

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 10 µg/mg protein lysate, Western Blot: 2 µg/mL

Aliases :

AI451004; AU020987; CCNC; CG1C; CycC; cyclin C; cyclin-C; dJ199J3.4 (cyclin C); hSRB11; SRB11 homolog